Results 121 to 130 of about 16,580 (214)

Higher plasma vitamin D levels are not causally associated with less age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Higher levels of plasma 25‐hydroxyvitamin D have been associated with a lower risk of age‐related macular degeneration (AMD). We investigated observational and potential causal associations of plasma 25‐hydroxyvitamin D with the risk of AMD in two large contemporary population‐based prospective studies and a genetic case–control ...
Sabina O. Beheshti   +3 more
wiley   +1 more source

External Venous Drainage (EVD) System: A Standardized Bedside Technique for Venous Congestion in Free Flaps. [PDF]

open access: yesClin Case Rep
Marcasciano M   +7 more
europepmc   +1 more source

Occurrence, progression and risk factors of macular atrophy in neovascular age‐related macular degeneration according to neovascularization subtypes

open access: yesActa Ophthalmologica, EarlyView.
Abstract Objective To assess the occurrence, risk factors, and progression of macular atrophy (MA) according to macular neovascularization (MNV) subtype in neovascular AMD (nAMD). Methods This multicentre retrospective observational cohort study included 416 eyes with nAMD, followed for at least 12 months and treated with anti‐VEGF.
Amandine Moulin   +11 more
wiley   +1 more source

CD93—An emerging vascular target in cancer therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira   +3 more
wiley   +1 more source

The road ahead for stem cell therapies in type 1 diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Type 1 diabetes results from autoimmune destruction of insulin‐producing pancreatic β‐cells. Although exogenous insulin remains the standard treatment, it does not restore physiological glucose regulation. Differentiation of human pluripotent stem cells into β‐cells offers a scalable alternative to cadaveric islet transplantation and has ...
Rosa Gasa   +2 more
wiley   +1 more source

USP25 promotes ferroptosis in diabetic retinopathy by deubiquitinating p53 and suppressing the GPX4/SLC7A11 axis

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the expression of the deubiquitinase (DUB) USP25 in diabetic retinopathy (DR) and its mechanistic role in regulating ferroptosis. Methods Bioinformatics was used to screen for DR‐related DUB candidate genes. USP25 expression was validated in a streptozotocin‐induced diabetic mouse model and high glucose (HG)‐treated ARPE ...
Yanjun Gao   +3 more
wiley   +1 more source

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