Results 121 to 130 of about 3,630,760 (297)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Postnatal refinement of gravity-related spatial coding to the central vestibular circuitry

open access: yes, 2009
The 36th International Congress of Physiological Sciences (IUPS2009), Kyoto, Japan, 27 July-1 August 2009. In Journal of Physiological Sciences, 2009, v. 59 suppl.
Han, L   +6 more
core  

Physiological and Transcriptome Analysis of Drought-Tolerant Mutant ds-1 of Blue Fescue (Festuca glauca) Under Drought Stress

open access: yesInternational Journal of Plant Biology
Blue fescue (Festuca glauca) is a widely used ornamental grass worldwide. Drought is an important limiting factor for the growth and development of blue fescue; therefore, cultivating new strains of blue fescue with a strong drought tolerance is of great
Yong Zhang   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Influences of Sex and Activity Level on Physiological Changes in Individual Adult Sockeye Salmon during Rapid Senescence

open access: yes, 2010
A noninvasive biopsy protocol was used to sample plasma and gill tissue in individual sockeye salmon (Oncorhynchus nerka) during the critical life stage associated with spawning-arrival at a spawning channel through senescence to death several days later.
Hinch, Scott G.   +5 more
core   +1 more source

Clinical application of abdominal breathing training and evaluation of physical and mental benefits in anxiety patients

open access: yesFrontiers in Psychology
BackgroundAnxiety disorders represent highly prevalent mental health conditions globally (lifetime prevalence: ~7–14%). Current pharmacological treatments carry risks of dependence and metabolic side effects, while psychological therapies face ...
Jiajin Chai   +8 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Effects of Non-Steady-State Noise on Pain, Anxiety and Stress Indicators in Patients Waiting for Coronary Angiography

open access: yesNoise and Health
Objective: To investigate the effect of non-steady-state noise on pain, anxiety and stress levels in patients waiting for coronary angiography. Methods: A retrospective analysis was conducted on the clinical records of 310 patients who had undergone ...
Tong Sun, Xintao Li, Minna Fan
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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