Results 111 to 120 of about 3,630,760 (297)

Improving Rice Genetic Resources by Conducting Differential Crossings to Create New Hybrids in Both Regular and Water- Deficient Conditions [PDF]

Journal of Plant Production
Thirty-six genotypes (8 parents and 28 F1s excluding reciprocals) were grown in a randomized complete block design (RCBD) with three replications at the Rice Research experimental farm, Sakha, Kafr El-Sheikh, Egypt, in 2022 and 2023 seasons. The ratio of
S. El-Naem, E. Daher, M. Ghazy, H. Hassan   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Studies from the Laboratory of Physiological Chemistry /

, 1885
Mode of access: Internet.Vol.
Chittenden, R. H. (Russell Henry), 1856-1943., Yale College (1718-1887). Laboratory of Physiological Chemistry., Yale University. Laboratory of Physiological Chemistry.   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Miniature inhibitory postsynaptic current in cerebellar Purkinje cells of old dystrophic mdx mice

, 2018
Duchenne muscular dystrophy (DMD) is caused by the mutations in the X-linked dystrophin gene resulting in a deficiency in the protein dystrophin. About 1/3 of boys with DMD display some degree of cognitive impairments (Cotton et al., 2001).
Tan, Chek Ying (S33333), Morley, John W. (R12018), Head, Stewart I. (R14226), Kueh, Sindy L. L. (R14227)   +3 more
core  

Unraveling the impact of water deficit stress on nutritional quality and defense response of tomato genotypes

Frontiers in Plant Science
Water deficit stress triggers various physiological and biochemical changes in plants, substantially affecting both overall plant defense response and thus nutritional quality of tomatoes.
Ayesha Wadood, Ayesha Wadood, Amjad Hameed, Amjad Hameed, Saba Akram, Saba Akram, Maria Ghaffar, Maria Ghaffar   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Cannabinoid receptor 2 expression in proximal tubule cells exposed to elevated glucose and albumin

, 2012
Introduction. Hyperglycaemia plays a significant role in the aetiology of diabetic nephropathy. Compounded with this, renal tubule cells are also exposed to high levels of albumin in the filtrate, which is caused by damage to the glomerulus.
McAinch, Andrew J., Hryciw, Deannne H., Jenkin, Kayte A. (R19563)   +2 more
core  

Hypoglycemic Ability of Sericin-Derived Oligopeptides (SDOs) from Bombyx mori Yellow Silk Cocoons and Their Physiological Effects on Streptozotocin (STZ)-Induced Diabetic Rats

Foods
Patients with diabetes require daily medication to maintain blood sugar levels. Nevertheless, the long-term use of antidiabetics can lose efficacy and cause degeneration in some patients. For long-term diabetes care, integrating natural dietary foods and
Chainarong Tocharus, Manote Sutheerawattananonda   +1 more
doaj   +1 more source