Results 81 to 90 of about 2,377,014 (266)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Physiology in Perspective: The Importance of Integrative Physiology [PDF]
Physiology, 2017 “The doctor of the future will give no medicine, but will interest his (her) patients in the care of the human frame, in diet, and in the cause and prevention of disease.” This comment, attributed to Thomas Edison, presaged the modern concepts of managed health care, health ...
openaire +2 more sources
Physiological Changes and Time-Course Transcriptomic Analysis of Salt Stress in Chenopodium quinoa
BiologyQuinoa, a halophytic pseudocereal crop, is highly resistant to harsh growing environments and is considered a suitable crop for cultivation in marginal areas.
Peipei Li, Yemeng Zhang
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Physiology in Perspective: The Value of Integrative Physiology [PDF]
Physiology, 2017 Almost a year ago, I gained a close and personal appreciation for the value gained from an understanding of integrative physiology. Suddenly one morning, while on vacation, I was struck by a massive pulmonary embolism and experienced first hand the importance of the interaction between the ...
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Effective Factors on Physiological Responses of Premature Infants to Holly Quran Recitation
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011 Background and Objectives: With regard to the importance of complementary therapy in premature infants and also the insufficient studies in this regard, this study was conducted in order to examine the effect of holly Quran recitation and effective ...
N Eskandari, M Keshavars, F Jahdi
doaj
LifeBackground: The impact of muscle-training treatment on quality of life and functional outcomes in people with pelvic floor dysfunction may be related to adherence rates.
Inmaculada Villa-Del-Pino +4 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
AnimalsAdaptation is one of the fundamental characteristics of life activities; humans and animals inhabiting high altitudes are well adapted to hypobaric hypoxic environments, and studies on the mechanisms of this adaptation emerged a hundred years ago.
Pengfei Zhao +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source