Results 151 to 160 of about 331,675 (261)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Unravelling the grey zone: submaximal-to-peak stress echocardiography enhances diagnostic accuracy in differentiating early dilated cardiomyopathy from physiological adaptation. [PDF]

Echo Res Pract
Marwaha SK, Basu J, Bhatia R, Maclachlan H, Fyyaz S, Esteban MTT, Behr ER, Finocchiaro G, Malhotra A, Prasad S, Gati S, Papadakis M, Sharma S.   +12 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Contrasting physiological adaptation strategies to natural environmental change in two Red Sea coral holobionts. [PDF]

ISME Commun
Thobor BM, Hill CEL, Custer GF, Garcias-Bonet N, Fox MD, El-Khaled YC, Aylagas E, Dini-Andreote F, Struck U, Tilstra A, Peixoto R, Carvalho S, Wild C, Mueller B.   +13 more
europepmc   +1 more source

Physiological Adaptation of Three Wild Halophytic Suaeda Species: Salt Tolerance Strategies and Metal Accumulation Capacity. [PDF]

Plants (Basel), 2022
Ibraheem F, Al-Zahrani A, Mosa A.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Comprehensive analysis of salt tolerance mechanisms in forage maize: physiological adaptation, transcriptional regulation, and key gene identification. [PDF]

BMC Plant Biol
Jiang Q, Yi D, Zhang S, Chen C, Zhou X, Cui Y, Liu Z, Zhi J, Ma L, Wang X.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Seasonal Plasticity in Tryptophan Metabolism Provides New Insights Into Physiological Adaptation in Snake Hibernation. [PDF]

Ecol Evol
Wei Y, Zhang Z, Lin X, Wei G, Zhang P, Mao H, Chen B, Ji J, Zheng Y, Luo Z, Hu X.   +10 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source