Results 41 to 50 of about 305,494 (292)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Novel insights into sex-specific differences in heart rate variability and autonomic nervous system regulation during spawning behavior in chum salmon (Oncorhynchus keta) revealed by re-analysis of ECG logger data

Frontiers in Physiology
This study reanalysed electrocardiogram (ECG) data collected in a previous study on chum salmon to explore sex-specific differences in heart rate variability (HRV) and autonomic nervous system regulation during spawning.
Yuya Makiguchi, Takaaki K. Abe, Masaki Ichimura   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Use of Myocardial Work in Athletes: A Novel Approach to Assess Cardiac Adaptations and Differentiate Physiological Remodeling from Pathology

Applied Sciences
Myocardial work (MW), derived from non-invasive pressure–strain loop (PSL) analysis, has recently emerged as a promising echocardiographic index for assessing left ventricular performance.
Simona Mega, Chiara Fossati, Andrea Segreti, Riccardo Cricco, Zlatan Lazarevic, Myriam Carpenito, Federica Coletti, Jacopo Valeri, Erika Lemme, Fabio Pigozzi, Francesco Grigioni   +10 more
doaj   +1 more source

Woody breast myopathy broiler show age-dependent adaptive differential gene expression in Pectoralis major and altered in-vivo triglyceride kinetics in adipogenic tissues

Poultry Science, 2021
: A study was conducted to understand the differentially expressed genes in Pectoralis (P) major under woody breast (WB) myopathy condition in a high yielding broiler strain using RNA-sequencing at the growing (d 21) and finishing (d 42 and d 56) grow ...
Pramir Maharjan, Antonio Beitia, Jordan Weil, Nawin Suesuttajit, Katie Hilton, Justina Caldas, Cole Umberson, Diego Martinez, Byungwhi Kong, Casey M. Owens, Craig Coon   +10 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Physiological responses of children with surgically corrected congenital heart disease during high-altitude trekking: an exploratory observational study

Frontiers in Pediatrics
BackgroundChildren with surgically corrected congenital heart disease (CHD) are often perceived as fragile and discouraged from engaging in physical activity, despite evidence that structured exercise improves functional capacity and quality of life ...
Kwang Ho Choi, Woong-Han Kim, Woong-Han Kim, Ja-Kyoung Yoon   +3 more
doaj   +1 more source

Physiological adaptation in savanna ungulates [PDF]

Proceedings of the Nutrition Society, 1997
Savannas lie between the equatorial rain forests and the semi-deserts of the southern continents. From the herbivore’s viewpoint, the savanna environment is characterized by a mixture of herbaceous and woody vegetation, varying in quantity and growth stage according to the seasonal cycle of rainfall. C4 grasses (i.e.
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A physiological adaptation to undernutrition

Annals of Human Biology, 1994
A total of 432 children under the age of 10 years were measured for height and weight, and the morbidity and mortality indices were studied in six counties of the maize region of the state of Yucatán, Mexico. Undernutrition, because of its relationship to morbidity and mortality, was considered an important selection factor operating between the ages ...
G, Balam, F, Gurri
openaire   +2 more sources