Results 61 to 70 of about 2,705,847 (301)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Supporting evidence-based adaptation decision-making in Western Australia: a synthesis of climate change adaptation research [PDF]

open access: yes, 2013
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Laura Cacho   +2 more
core  

Screening shade-tolerant centipedegrass genotypes: Physiological and transcriptomic insights into shade adaptation mechanisms

open access: yesGrass Research
Shade stress is a major constraint for the growth and performance of turfgrass in urban environments. To investigate shade tolerance mechanisms in centipedegrass (Eremochloa ophiuroides), we evaluated 16 genotypes under 66% and 99% shading for 18 d. CP11
Yiming Liu   +7 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Barriers to adaptation to sea-level rise [PDF]

open access: yes, 2013
Increasingly there is recognition from researchers and policy makers that there are legal, institutional and cultural barriers to climate change adaptation that will need to be addressed if we are able to adapt efficiently and equitably.
Elissa Waters   +2 more
core  

physiological adaptation

open access: yes
Citation: 'physiological adaptation' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14916 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Sajad Hussain Parey   +2 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Responses and adaptations of collembolan communities (Hexapoda: Collembola) to flooding and hypoxic conditions Respostas e adaptações de comunidades de colêmbolos (Hexapoda: Collembola) a condições de inundação e hipoxia

open access: yesPesquisa Agropecuária Brasileira, 2009
Standard ecological methods (pitfall traps, trunk eclectors and soil cores) were used to evaluate collembolan community responses to different flooding intensities.
Michael Thomas Marx   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Combined physical activity in the prevention of cardiovascular diseases: from physiological to molecular adaptation mechanisms

open access: yesКлиническая практика
Physical activity is recognized as the most important non-medicinal tool for the prevention of cardiovascular diseases, however, the highest efficiency is demonstrated by the programs combining various types of physical load.
Abduragim R. Magomedov   +12 more
doaj   +1 more source

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