Results 61 to 70 of about 2,569,018 (257)
Клиническая практикаPhysical activity is recognized as the most important non-medicinal tool for the prevention of cardiovascular diseases, however, the highest efficiency is demonstrated by the programs combining various types of physical load.
Abduragim R. Magomedov +12 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Climate change adaptation in the boardroom [PDF]
, 2013 Climate adaptation is recognised by many of the world’s largest businesses as a global risk and one that requires critical attention. The World Economic Forum’s 2013 Global Risks Perception Survey, identified the ‘failure of climate change adaptation and
Mark Baker-Jones +2 more
core
Physiological Genomics of Temperature Adaptation among Natural Fundulus heteroclitus Populations
, 2023 Adaptation acting on physiological processes may occur if temperature differences are consistent, and drift is low. Yet characterizing temperature adaptation is challenging and an integrative approach combining physiological, molecular, and genomic data ...
DeLiberto, Amanda
core +4 more sources
Cogent Social SciencesSprint kayaking performance benefits from training strategies matched to athletes’ physiological profiles and race demands. This study examined the effects of the Effort Dynamics Control Methodology (EDCM)—a metabolically anchored, feedback-driven model ...
Aurel Alecu +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Supporting evidence-based adaptation decision-making in the Australian Capital Territory: a synthesis of climate change adaptation research [PDF]
, 2013 This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Jennifer Cane
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Joining the dots: hydrology, freshwater ecosystem values and adaptation options [PDF]
, 2013 The objective of this research was to investigate and test the necessary steps in developing an adaptation planning framework for freshwater biodiversity.
Leon Barmuta, Peter Davies, Anne Watson
core
, 2011 In the present study, we analysed the training-intensity distribution and physiological adaptations over a 6-month period preceding an Ironman triathlon race.
Galloway, S D +5 more
core +1 more source