Results 81 to 90 of about 2,705,847 (301)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Valuing adaptation under rapid change [PDF]

open access: yes, 2013
The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young   +2 more
core  

Role of Modified Atmosphere in Pest Control and Mechanism of Its Effect on Insects

open access: yesFrontiers in Physiology, 2019
Pests not only attack field crops during the growing season, but also damage grains and other food products stored in granaries. Modified or controlled atmospheres (MAs or CAs) with higher or lower concentrations of atmospheric gases, mainly oxygen (O2),
Yu Cao   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Decision-making for climate change adaptation: A systems thinking approach [PDF]

open access: yes, 2013
The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core  

Explaining bathymetric diversity patterns in marine benthic invertebrates and demersal fishes: physiological contributions to adaptation of life at depth

open access: yes, 2014
Bathymetric biodiversity patterns of marine benthic invertebrates and demersal fishes have been identified in the extant fauna of the deep continental margins.
Brown, Alastair, Thatje, Sven
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Supporting evidence-based adaptation decision-making in the Australian Capital Territory: a synthesis of climate change adaptation research [PDF]

open access: yes, 2013
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Jennifer Cane
core  

Analysis of the Alterations in Symbiotic Microbiota and Their Correlation with Intestinal Metabolites in Rainbow Trout (Oncorhynchus mykiss) Under Heat Stress Conditions

open access: yesAnimals
Global warming represents one of the most pressing environmental challenges to cold-water fish farming. Heat stress markedly alters the mucosal symbiotic microbiota and intestinal microbial metabolites in fish, posing substantial barriers to the healthy ...
Changqing Zhou, Fengyuan Ding
doaj   +1 more source

Exercise and Training at Altitudes: Physiological Effects and Protocols

open access: yesRevista Ciencias de la Salud, 2014
An increase in altitude leads to a proportional fall in the barometric pressure, and a decrease in atmospheric oxygen pressure, producing hypobaric hypoxia that affects, in different degrees, all body organs, systems and functions.
Olga Cecilia Vargas Pinilla
doaj   +1 more source

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