Results 91 to 100 of about 2,569,018 (257)
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The Classic-Novel Adaptation from 1995 to 2009 [PDF]
This thesis explores the dynamic relationship between the nineteenth-century novel and the screen, interrogating evolving trends in film and television adaptation from the mid-1990s to 2009.
WHITE, REBECCA,ARWEN
core
Modeling flexible behavior with remapping-based hippocampal sequence learning
Animals flexibly change their behavior depending on context. It is reported that the hippocampus is one of the most prominent regions for contextual behaviors, and its sequential activity shows context dependency.
Yoshiki Ito, Taro Toyoizumi
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Climate change adaptation for Australian minerals industry professionals [PDF]
Extreme weather events in Australia over recent years have highlighted the costs for Australian mining and mineral processing operations of being under-prepared for adapting to climate risk.
Leah Mason +3 more
core
Spontaneous ovarian hyperstimulation syndrome (OHSS) is closely associated with follicle stimulating hormone receptor (FSHR) functional mutations. We observed that estrildid finches naturally carry the gain‐of‐function FSHR p.Thr449Ala mutation found in ...
Xiaofei Yan +11 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Adaptor of last resort? An economic perspective on the government’s role in adaptation to climate change [PDF]
Individuals and societies have always adapted to change, whether catastrophic or slow onset. Over the last two centuries, however, governments have significantly extended their role as ultimate social manager of risk.
Leo Dobes, Patrick Doupe, Frank Jotzo
core
Adaptation at scale in semi-arid regions [PDF]
French version available in IDRC Digital Library: Adaptation à différentes échelles dans les régions semi-aridesWorking with stakeholders from Botswana, India, Ethiopia, Ghana, Kenya, Mali, Namibia, and Uganda, the Adaptation at Scale in Semi-Arid ...
IDRC. Collaborative Adaptation Research Initiative in Africa and Asia (CARIAA)
core +1 more source

