Results 91 to 100 of about 2,705,847 (301)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Climate change adaptation in the boardroom [PDF]

open access: yes, 2013
Climate adaptation is recognised by many of the world’s largest businesses as a global risk and one that requires critical attention. The World Economic Forum’s 2013 Global Risks Perception Survey, identified the ‘failure of climate change adaptation and
Mark Baker-Jones   +2 more
core  

Biophysical and Physiological Responses promoting Freeze Tolerance in Vertebrates

open access: yes, 1994
Freeze tolerance, an overwintering adaptation of at least 10 species of ectothermic vertebrates, is promoted by integrated biophysical and physiological responses to ice forming within tissues.
JP Costanzo, RE, Lee
core   +1 more source

The physiological and psychosocial adaptation of individuals with insulin-dependent diabetes and non-insulin-dependent diabetes

open access: yes, 1994
The purpose of this descriptive study was to identify, describe, and compare the physiological and psychosocial adaptation of individuals with insulin dependent diabetes and non-insulin dependent diabetes.
Wortell, Linda
core   +3 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Comparative Adaptive Mechanisms of Two Indigenous Goat Genetic Resources Under Simulated Water Scarcity

open access: yesAnimals
Water scarcity is a major constraint to livestock production in tropical and semi-arid environments, necessitating the identification of breeds with superior adaptive capacity.
Oluwakamisi Festus Akinmoladun   +2 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Physiological plasticity and local adaptation to elevated pCO2 in calcareous algae: an ontogenetic and geographic approach [PDF]

open access: yes, 2016
To project how ocean acidification will impact biological communities in the future, it is critical to understand the potential for local adaptation and the physiological plasticity of marine organisms throughout their entire life cycle, as some stages ...
Hofmann, Gretchen E.   +15 more
core   +1 more source

Preliminary Data Regarding the Physiological State of Alosa immaculata (Bennett, 1835) During Spawning Migration

open access: yesAquaculture, Fish and Fisheries
Reproductive migration in anadromous fish involves complex physiological adjustments to support intense metabolic and reproductive demands. In the case of Alosa immaculata, a key migratory species of the lower Danube River, these adaptations can be ...
Angelica Dobre   +3 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

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