Results 101 to 110 of about 860,227 (306)

Physiological adaptations and functional changes in young soccer players' organisms aged 11-14 years following a 12-week specialized training program: a sports medicine perspective

Medičnì Perspektivi
This study investigated the physiological adaptations and functional conse­quences of a 12-week specialized training program in youth soccer players, focusing on musculoskeletal development, cardiorespiratory responses, and neuromuscular adaptations ...
I. Grygus , M. Grynova , T. Gamma , P. Hodlevskyi , W. Zukow   +4 more
doaj   +1 more source

Responses and adaptations of collembolan communities (Hexapoda: Collembola) to flooding and hypoxic conditions Respostas e adaptações de comunidades de colêmbolos (Hexapoda: Collembola) a condições de inundação e hipoxia

Pesquisa Agropecuária Brasileira, 2009
Standard ecological methods (pitfall traps, trunk eclectors and soil cores) were used to evaluate collembolan community responses to different flooding intensities.
Michael Thomas Marx, Anna-Katharina Wild, Ulrich Knollmann, Günter Kamp, Gerhard Wegener, Gerhard Eisenbeis   +5 more
doaj   +1 more source

Adaptation of Binaural Processing in the Adult Brainstem Induced by Ambient Noise [PDF]

, 2012
Interaural differences in stimulus intensity and timing are major cues for sound localization. In mammals, these cues are first processed in the lateral and medial superior olive by interaction of excitatory and inhibitory synaptic inputs from ipsi- and ...
Grothe, Benedikt, Leibold, Christian, Schiller, Evelyn, Siveke, Ida   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Physiological responses to prolonged bed rest in humans: A compendium of research, 1981-1988 [PDF]

Clinical observations and results form more basic studies that help to elucidate the physiological mechanisms of the adaptation of humans to prolonged bed rest. If the authors' abstract or summary was appropriate, it was included.
Barnes, Paul R., Greenleaf, John E., Luu, Phuong B., Ortiz, Vanessa   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Editorial: Abiotic stress alleviation in plants: morpho-physiological and molecular aspects

Frontiers in Plant Science, 2023
Mahmoud Magdy, Mahmoud Magdy, Mohammad Golam Mostofa, Mohammad Golam Mostofa, Mehdi Rahimi, Diaa Abd El Moneim   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The 4Rs Framework of Sports Nutrition: An Update with Recommendations to Evaluate Allostatic Load in Athletes

Life
The 4Rs of sports nutrition were proposed in recent years as an evidence-based framework to optimize post-exercise recovery within the context of allostasis.
Diego A. Bonilla, Jeffrey R. Stout, Michael Gleeson, Bill I. Campbell, Guillermo Escalante, Daniel Rojas-Valverde, Jorge L. Petro, Richard B. Kreider, Adrián Odriozola-Martínez   +8 more
doaj   +1 more source