Results 101 to 110 of about 2,705,847 (301)

Estrogen deficiency alters skeletal and metabolic responses to obesity and weight loss strategies

open access: yesBone Reports, 2020
Maude Gerbaix   +7 more
doaj   +1 more source

Stress-Induced Metabolic Reprogramming in the Green Microalga Chlorella sp. SLA-04

open access: yesMicroorganisms
Microalgae thrive in diverse and often challenging environments by coordinating metabolic and physiological responses to environmental stress, yet the molecular mechanisms underlying these adaptations remain incompletely understood.
Calvin L. C. Goemann   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Resting Heart Rate Responses After Three Months of Intensive Exercise

open access: yesJournal of Sport Science and Fitness
Introduction: Resting heart rate (RHR) is a key indicator of cardiovascular adaptation in athletes, reflecting physiological responses to intensive training.
Diaz Irfansyah Diaz   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

open access: yesAdvanced Science
Spontaneous ovarian hyperstimulation syndrome (OHSS) is closely associated with follicle stimulating hormone receptor (FSHR) functional mutations. We observed that estrildid finches naturally carry the gain‐of‐function FSHR p.Thr449Ala mutation found in ...
Xiaofei Yan   +11 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Learning from cross-border mechanisms to support climate change adaptation in Australia [PDF]

open access: yes, 2013
The impacts of climate change do not adhere to conventional governance boundaries. Floods for example do not stop at the state border, nor are storm surges contained within local government jurisdictions.
Wendy Steele
core  

Integrated effects of cold acclimation: physiological mechanisms, psychological adaptations, and potential applications

open access: yesFrontiers in Physiology
Cold acclimation refers to the gradual process by which individuals adapt to cold environments. With the increasing impact of global climate change and the growing popularity of extreme sports, research on cold acclimation has attracted significant ...
Yongxing Wang   +7 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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