Results 111 to 120 of about 13,726,255 (344)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Personal Identification and the Assessment of the Psychophysiological State While Writing a Signature

Information, 2015
This article discusses the problem of user identification and psychophysiological state assessment while writing a signature using a graphics tablet. The solution of the problem includes the creation of templates containing handwriting signature features
Pavel Lozhnikov, Alexey Sulavko, Alexander Samotuga   +2 more
doaj   +1 more source

Heart Rate Variability: New Perspectives on Physiological Mechanisms, Assessment of Self-regulatory Capacity, and Health risk

Global Advances in Health and Medicine, 2015
Heart rate variability, the change in the time intervals between adjacent heartbeats, is an emergent property of interdependent regulatory systems that operates on different time scales to adapt to environmental and psychological challenges. This article
R. McCraty, F. Shaffer
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Physiological assessment of long pepper seeds

Revista de Ciências Agroambientais, 2015
The environmental and economic potential of long pepper (Piper hispidinervum) requires the development of methodology to evaluate seed potential physiological.
Francisco Pacheco Júnior, Josué Bispo da Silva, Jacson Rondinelli da Silva Negreiros, Charline Zaratin Alves, Marco Antônio Camillo de Cavalho   +4 more
doaj  

Collaborative assessment and the assessment of collaboration

, 2012
Anecdotal evidence suggests that while learning through group work and evaluation through group assessment are common in primary schools, this trend tapers in secondary, and virtually disappears in the latter years of secondary school and through into ...
McAlpine, Mhairi
core  

Mobile distributed processing of physiological data [PDF]

, 2012
Physiological monitoring can be useful in a number of scenarios to evaluate or diagnose the status of individuals or groups, for health or mental reasons.
Lee, K., Meneghello, J., Gilleade, K., Kevin Lee, Kiel Gilleade, James Meneghello   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source