Results 181 to 190 of about 13,726,255 (344)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The ultrasound gap in de-resuscitation trials: A systematic review of physiological assessment deficits. [PDF]

Ultrasound J
Wong A, Melo P, Stefanini F, Cheah K, Kattan E, Zawadka M.   +5 more
europepmc   +1 more source

The strategic importance of policy development to successful e-assessment implementation

, 2012
Successful e-assessment implementation is in large part dependent on the development of a clear policy framework around which practice can establish, embed and mature.
Walker, David
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Role of Preoperative Physiological Assessment: A Step Forward in Planning, Not Yet in Outcomes. [PDF]

JACC Asia
Ninomiya K, Tosaka K.
europepmc   +1 more source

Physiological Assessment of the Health and Welfare of Domestic Cats-An Exploration of Factors Affecting Urinary Cortisol and Oxytocin. [PDF]

Animals (Basel), 2022
Nagasawa T, Kimura Y, Masuda K, Uchiyama H.   +3 more
europepmc   +1 more source

Pilot of adaptive comparative judgement within Sociology: full report

, 2014
Report on a pilot project commissioned by College Development Network (CDN) to investigate the potential for the use of an innovative assessment methodology called Comparative Judgement in the delivery of coursework and essay assessment as part of the ...
TAG Assessment
core  

CMA-ECG: cross-modal attention for enhanced ECG quality assessment and denoising

Objective.Electrocardiogram (ECG) analysis is vital for the diagnosis of cardiac conditions and monitoring human physiological states. However, challenges such as signal perturbations, inconsistent quality, and signal inference undermine the reliability ...
Nguyen, Hong Duc, Phan, Duc Tri
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Coronary physiological assessment in the catheter laboratory: haemodynamics, clinical assessment and future perspectives. [PDF]

Heart, 2022
Morris PD, Al-Lamee RK, Berry C, BCIS Research and Development Committee.   +3 more
europepmc   +1 more source