Results 61 to 70 of about 1,699,941 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Physiological and Clinical Assessment of Resting Physiological Indexes. [PDF]

Circulation, 2019
Recently, resting pressure-derived indexes such as resting full-cycle ratio (RFR) and diastolic pressure ratio (dPR) have been introduced to assess the functional significance of epicardial coronary stenosis. The present study sought to investigate the agreement of RFR or dPR with other pressure-derived indexes (instantaneous wave-free ratio [iFR] or ...
Joo Myung, Lee, Ki Hong, Choi, Jonghanne, Park, Doyeon, Hwang, Tae-Min, Rhee, Jinseob, Kim, Jinhyoung, Park, Hyung Yoon, Kim, Hae Won, Jung, Yun-Kyeong, Cho, Hyuck-Jun, Yoon, Young Bin, Song, Joo-Yong, Hahn, Chang-Wook, Nam, Eun-Seok, Shin, Joon-Hyung, Doh, Seung-Ho, Hur, Bon-Kwon, Koo   +17 more
openaire   +3 more sources

Quantitative magnetic resonance image analysis via the EM algorithm with stochastic variation

, 2008
Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and determine optimal ...
Cao, Yue, Johnson, Timothy D., Little, Roderick J. A., Zhang, Xiaoxi   +3 more
core   +1 more source

Swallowing impairment in neurologic disorders : the role of videofluorographic swallowing study [PDF]

, 2018
Patients with neurologic diseases almost inevitably develop various degrees of swallowing disorders during their life. Dysphagia is one of the main negative prognostic factors in this class of patients, leading to severe morbidity (i.e.

core   +1 more source

Assessment of physiological upper eyelid laxity

Journal Français d'Ophtalmologie, 2019
To evaluate overall upper eyelid laxity according to age and sleep position.This single-center prospective study was conducted on healthy subjects between 20 and 89 years of age and was approved by the institutional review board and the ethics committee.
M, Broussard, N, Leveziel, M, Lii, D, Tonnerre, R, Flausse   +4 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Assessment of acute physiological demand for soccer

Revista Brasileira de Cineantropometria e Desempenho Humano, 2013
Soccer is a sport practiced worldwide, on all continents. It is considered an intermittent activity of high intensity and long duration, in which movements that require great strength and speed, such as jumps and sprints, result in high levels of muscle ...
Daniel Barbosa Coelho, Eduardo Mendonça Pimenta, Christiano Eduardo Veneroso, Rodrigo Figueiredo Morandi, Diogo Antônio Soares Pacheco, Emerson Rodrigues Pereira, Leonardo Gomes Martins Coelho, Emerson Silami Garcia   +7 more
doaj   +1 more source

Entropy-Based Pattern Learning Based on Singular Spectrum Analysis Components for Assessment of Physiological Signals

Complexity, 2020
Measures of predictability in physiological signals based on entropy metrics have been widely used in the application domain of medical assessment and clinical diagnosis.
Yun Lu, Mingjiang Wang, Wanqing Wu, Qiquan Zhang, Yufei Han, Tasleem Kausar, Shixiong Chen, Ming Liu, Bo Wang   +8 more
doaj   +1 more source

Defective neural motor speech mappings as a source for apraxia of speech : evidence from a quantitative neural model of speech processing [PDF]

, 2011
This unique resource reviews research evidence pertaining to best practice in the clinical assessment of established areas such as intelligibility and physiological functioning, as well as introducing recently developed topics such as conversational ...
Kroger, Bernd, Lowit, Anja, Miller, N.
core  

Study protocol to investigate the effect of a lifestyle intervention on body weight, psychological health status and risk factors associated with disease recurrence in women recovering from breast cancer treatment [PDF]

, 2006
Background Breast cancer survivors often encounter physiological and psychological problems related to their diagnosis and treatment that can influence long-term prognosis.
A Campbell, A McTiernan, A McTiernan, A Silvestri, A Visser, AB Kornblith, AC Utter, AH Wu, AJ Daley, Amanda Daley, AN Dentino, AS Fairey, AT Beck, B Dugue, B Rockhill, B Zumoff, BL Andersen, BL Gruber, BL Stauffer, BM Pinto, BS McEwen, C Peters, C Peters, C Wiltschke, CB Ebbeling, CL Caldwell, CM Bryla, CM Friedenreich, D Geffken, D Nerozzi, DC McMillan, DC Nieman, DC Nieman, DC Nieman, DC Nieman, DC Nieman, DC Nieman, DF Cella, DG Cruess, DH Bovbjerg, DM Golden-Kreutz, DV Schapira, DW Kissane, E Maunsell, EA Bermudez, G Borg, G van der Pompe, G van der Pompe, GG Kolden, H Davis, H Kervinen, HC Abercrombie, Helen Crank, Hilary Powers, HV Thomas, J Gallagher, J Kaukua, J Verloop, JA Cauley, JE Bower, JE Epping-Jordan, JF Sallis, JK Camoriano, JK Smith, JO Prochaska, John M Saxton, JR Calabrese, JS Goodwin, KL Jen, KM Rexrode, KS Courneya, KS Madden, L Bernstein, L Chang, M Maes, M Maes, M Maes, M Mezzetti, MD Gammon, MD Holmes, MD Holmes, ME Nelson, MK Baldwin, N Banu, Nanette Mutrie, Nicola Woodroofe, PJ Goodwin, RJ Benschop, Robert Coleman, RT Chlebowski, S Cohen, S Levy, S Yamasaki, SE Hankinson, SE Sephton, SI Mannering, SJ Schleifer, SJH Biddle, SK Lutgendorf, SM Levy, T Moradi, T Treasure, TA Wadden, TP Erlinger, U Ehlert, Vanessa Siddall, Y Touitou, Y Touitou, Z Djuric, Z Kronfol   +109 more
core   +4 more sources