Results 81 to 90 of about 5,660,868 (261)

Assessment of physiological upper eyelid laxity

Journal Français d'Ophtalmologie, 2019
To evaluate overall upper eyelid laxity according to age and sleep position.This single-center prospective study was conducted on healthy subjects between 20 and 89 years of age and was approved by the institutional review board and the ethics committee.
Broussard, M., Leveziel, N., Lii, M., Tonnerre, D., Flausse, R.   +4 more
openaire   +4 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Physiological Vibration Acceleration (Phybrata) Sensor Assessment of Multi-System Physiological Impairments and Sensory Reweighting Following Concussion

Medical Devices: Evidence and Research, 2020
John D Ralston,1 Ashutosh Raina,2,3 Brian W Benson,4,5 Ryan M Peters,6,7 Joshua M Roper,1 Andreas B Ralston1 1PROTXX, Inc., Menlo Park, CA 94025, USA; 2Center of Excellence for Pediatric Neurology, Rocklin, CA 95765, USA; 3Concussion Medical Clinic ...
Ralston JD, Raina A, Benson BW, Peters RM, Roper JM, Ralston AB   +5 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Peer assessment assisted by technology

, 2012
A common theme from the National Student Survey is that students want more feedback, but increasing the amount of teacher-student feedback is not practicable. Peer assessment, if carefully supported, can be a cost-effective solution.
Barr, Niall, Hamer, John, Brown, C., Hamer, J., Honeychurch, Sarah, Brown, Craig, Honeychurch, S., Barr, N.   +7 more
core  

Physiological assessment of aerobic training in soccer

, 2005
Physiological assessment of soccer training usually refers to the measurement of anatomical, physiological, biochemical and functional changes specific to the sport discipline (training outcome).
Rampinini, E., Marcora, S. M., Impellizzeri, F. M., Marcora, SM, Impellizzeri, FM, Rampinini, E   +5 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

CMA-ECG: cross-modal attention for enhanced ECG quality assessment and denoising

Objective.Electrocardiogram (ECG) analysis is vital for the diagnosis of cardiac conditions and monitoring human physiological states. However, challenges such as signal perturbations, inconsistent quality, and signal inference undermine the reliability ...
Nguyen, Hong Duc, Phan, Duc Tri
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source