Results 71 to 80 of about 1,047,266 (265)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Dual Inoculations of Dark Septate Endophytic and Ericoid Mycorrhizal Fungi Improved the Drought Resistance of Blueberry (Vaccinium corymbosum L.) Seedlings

Journal of Fungi
Dark septate endophytes (DSE) and ericoid mycorrhizal fungi (ERMF) are employed to augment the abiotic stress resistance of fruits. However, their potential functions in enhancing the drought resistance of blueberry, an economically important fruit ...
Xiaolan Guo, Jinbin Hu, Yaqin Wang, Lingda Zeng, Dun Wang, Yu Cao, Delu Wang   +6 more
doaj   +1 more source

[Physiological characteristics of pneumococci].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1982
The physiological activity of pneumococci under different physico-chemical conditions of deep cultivation in a liquid culture medium has been studied. The culture has been shown to achieve its maximum physiological activity under the conditions of neutral pHn-7.0) and the minimum content of dissolved oxygen in the medium.
I M, Gruber, L G, Zhdanova, Iu V, Mokhov, I D, Gorbachev, A K, Vargina   +4 more
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Selenite alleviates PEG-induced drought stress during rice seed germination through antioxidant regulation and osmotic adjustment

Plant, Soil and Environment
Drought stress severely impairs seed germination. Selenium (Se) is a potential mitigator of abiotic stress, but its physiological mechanisms in alleviating osmotic stress during seed germination remain poorly understood.
Ying Wang, Qing Zhu, Xue Luo, Gaogao Dai, Jingwen Hou, Feiyan Yu, Lianhe Zhang   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Optimizing Potassium Reduction with Polyhalite Blends for High Potato Yield and Nutrient Efficiency

Agronomy
In Inner Mongolia, a major potato-producing region of China, suboptimal potassium (K) fertilization often compromises tuber quality and affects yield. A two-year field study (2022–2023) evaluated the effects of different K application rates and blending ...
Dong Wang, Yaoyao Gai, Zhiping Li, Yan Shi, Chong Du, Xiaojie Luan, Xinyao Shi, Ziyi Zhang   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source