Results 51 to 60 of about 2,694,160 (314)
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance The circadian clock is an endogenous molecular timekeeper that coordinates biological rhythms of physiological and developmental processes in living organisms.
J. Cha +15 more
semanticscholar +1 more source
Compensation due to age-related decline in sit-to-stand and sit-to-walk.
Journal of Biomechanics, 2021 Capacity is the physiological ability of the neuromusculoskeletal systems; this declines with age. This decline in capacity may result in the inability to stand up (sit-to-stand, sit-to-walk), which is an important movement for independent living ...
Eline van der Kruk +3 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Physiological changes of premotor nonspiking interneurons in the central compensation of eyestalk posture following unilateral sensory ablation in crayfish [PDF]
, 2007 We investigated how the physiological characteristics and synaptic activities of nonspiking giant interneurons (NGIs), which integrate sensory inputs in the brain and send synaptic outputs to oculomotor neurons innervating eyestalk muscles, changed after
Takahata, Masakazu, Fujisawa, Kenichi
core +1 more source
Molecular Mechanisms Regulating Temperature Compensation of the Circadian Clock
Frontiers in Neurology, 2017 An approximately 24-h biological timekeeping mechanism called the circadian clock is present in virtually all light-sensitive organisms from cyanobacteria to humans.
David M. Virshup, Rajesh Narasimamurthy
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Molecular Systems Biology, 2013 Circadian clocks exhibit ‘temperature compensation’, meaning that they show only small changes in period over a broad temperature range. Several clock genes have been implicated in the temperature‐dependent control of period in Arabidopsis.
Peter D Gould +13 more
doaj +1 more source
Frontiers in Human Neuroscience, 2023 Strong cognitive regulation is advantageous for flexible, responsive parenting. Optimal cognitive regulation is reliant on associations between physiological mechanisms of central and peripheral nervous system functioning.
Jennifer D. Christensen +2 more
doaj +1 more source
Ecology Letters, 2021 Alpine large herbivores have developed physiological and behavioural mechanisms to cope with fluctuations in climate and resource availability that may become maladaptive under climate warming. We tested this hypothesis in female Alpine ibex (Capra ibex)
P. Semenzato +7 more
semanticscholar +1 more source