Results 61 to 70 of about 2,694,160 (314)
Human-Machine Compatibility of the Elbow Exoskeleton Robot Axis Misalignment Problem and Compensation Mechanism [PDF]
With the increasing burden of neurological diseases and the aging population, the need for efficient upper limb rehabilitation is becoming increasingly urgent.
Yun Jiacheng
doaj +1 more source
Introduction: Physiological aging frequently leads to degenerative changes and spinal deformity. In patients with hypolordotic fusions or ankylosing illnesses such as diffuse idiopathic skeletal hyperostosis or ankylosing spondylitis, compensation ...
Victor Garcia-Martin MD +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Resource allocation, hyperphagia and compensatory growth
Organisms often shown enhanced growth during recovery from starvation, and can even overtake continuously fed conspecifics (overcompensation). In an earlier paper (Ecology 84, 2777-2787), we studied the relative role played by hyperphagia and resource ...
Gurney, W.S.C. +3 more
core +1 more source
Effect of limited supply of assimilates on the relationships between their sources and acceptors
Sink activity in young sunflower and bean plants was determined mainly by their growth rate. The organ with higher RGR (stem in sunflower and apical part with expanded trifoliate leaf- in bean plant) was the dominant acceptor even in conditions of ...
Z. Starck, L. Ubysz
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On the Use of a Test to Exhaustion Specific to Tennis (TEST) with Ball Hitting by Elite Players. [PDF]
We aimed to a) introduce a new Test to Exhaustion Specific to Tennis (TEST) and compare performance (test duration) and physiological responses to those obtained during the 20-m multistage shuttle test (MSST), and b) determine to which extent those ...
Cyril Brechbuhl +3 more
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
A Qualitative Investigation of Physical Activity Compensation Among Older Adults [PDF]
ObjectivesThis study explored the mechanisms of physical activity (PA) compensation among older adults who recently reduced their non-exercise physical activity (NEPA) in response to a structured PA intervention.DesignA post-trial, retrospective ...
Phillip Gray +8 more
core +1 more source
Determining habitat conditions that generate individual physiological variability represents key basic knowledge to understand the direction of animal's responses to habitat change.
JOSÉ M PULGAR +2 more
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