Results 81 to 90 of about 2,694,160 (314)

CO₂transport in normovolemic anemia: complete compensation and stability of blood CO₂tensions

, 1997
Deem, Steven A., Michael K. Alberts, Michael J. Bishop, Akhil Bidani, and Erik R. Swenson.CO2transport in normovolemic anemia: complete compensation and stability of blood CO2tensions. J. Appl. Physiol.
Michael J. Bishop, Michael K. Alberts, Steven Deem, Akhil Bidani, Erik R. Swenson   +4 more
core   +1 more source

Wrist Information Detection Sensor Based on Pinhole Imaging

IEEE Photonics Journal
For the purpose of meeting the requirements of wrist-worn wearable devices for human-computer interaction and for measuring human physiological parameters, especially dynamic physiological parameters, the collaborative work of various sensors is ...
Hongmin Qi, Jun Xiong, Meichen Cao, Weien Lai, Yaohui Hu   +4 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Temperature Compensation through Systems Biology

, 2007
Temperature has a strong influence on most individual biochemical reactions. Despite this, many organisms have the remarkable ability to keep certain physiological fluxes approximately constant over an extended temperature range.
Zakhartsev, Maxim, Westerhoff, H. V., Westerhoff, H.V., Ruoff, P., Westerhoff, H.V.; id_orcid, Zakhartsev, M.   +5 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Dual-path capacitance compensation network for microelectrode recordings

, 1980
Commercially available microelectrode preamplifiers have a built-in capacity compensation circuit. When a shielded cable is utilized to transmit the signal from the microelectrode to the preamplifier the compensative ability of this circuit may be ...
R. McGillivray, R. Wald
core   +1 more source

Molecular mechanisms of toxicity and detoxification of copper-ciprofloxacin complexes in lettuce (Lactuca sativa L.)

Environment International
Animal manures and organic fertilizers often contain elevated residues of transition metals (e.g., Cu and Zn) and antibiotics, and their complexation complicates the phytotoxicity evaluation and risk attribution in agricultural ecosystems.
Yimeng He, Hefa Cheng, Shu Tao
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source