Results 31 to 40 of about 6,062,383 (272)

Dietary nitrate reduces skeletal muscle oxygenation response to physical exercise : a quantitative muscle functional MRI study [PDF]

, 2014
© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc.
Gray, Stuart R, He, Jiabao, Dawson, D., Frenneaux, M., Schwarzbauer, Christian, Frenneaux, Michael, Bentley, R., Gray, S.R., He, J., Schwarzbauer, C., Gray, Stuart R., Dawson, Dana, Bentley, Rachel   +12 more
core   +1 more source

Upper temperature limits of tropical marine ectotherms: global warming implications [PDF]

, 2011
Animal physiology, ecology and evolution are affected by temperature and it is expected that community structure will be strongly influenced by global warming.
Peck, Lloyd S., Tan, Koh Siang, Lloyd S Peck, Lai Chien-Houng, Lai, Chien-Houng, Simon A Morley, Melody S Clark, Chien-Houng Lai, Clark, Melody S., Lai, C.-H., Morley, Simon A., Nguyen Khanh Dung T., Tan Koh Siang, Tan, K.S., Khanh Dung T Nguyen, Clark, M.S., Bates, Amanda E., Bates, A.E., Bates Amanda E., Clark Melody S., Peck Lloyd S., Koh Siang Tan, Nguyen, K.D.T., Peck, L.S., Amanda E Bates, Morley Simon A., Nguyen, Khanh Dung T., Morley, S.A.   +27 more
core   +2 more sources

Forecasting Human Bioclimatic Comfort in a Hot–Dry Climate Using Sarimax Machine Learning: Diyarbakır, Turkey

Atmosphere
Climate, and especially cities with hot climatic conditions, directly impact human life. In this study, hourly datasets from the central meteorological station in Diyarbakır city center for the years 1990–2022 were utilized.
Ahmet Koç, Murat Uçan, Sülem Şenyiğit Doğan, Mehmet Kaya, Gökhan Şahin, Erdal Akin   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Analysis of equivalent temperature - case of Kragujevac city [PDF]

, 2018
A more complete climate image of a site is obtained by analyzing bioclimatic indicators. In this paper, an analysis of the physiological sense of heat in the territory of the city of Kragujevac was presented.
Jovan Dragojlovic, Nikola Milentijevic, Kristina Kalkan, Dusan Ristic, Dragan Buric, Marija Cimbaljevic   +5 more
core   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Assessment of Physiological Equivalent Temperature (PET) in Transitional Spaces of a High-Rise Building [PDF]

Asian Journal of Behavioural Studies, 2018
One passive approach that can significantly reduce energy usage in high-rise buildings is through the creation of non-air conditioned spaces such as transitional spaces. Optimizing passive design would reduce wastage associated with the building’s energy consumption.
openaire   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Use of a mobile platform for assessing urban heat stress in Rotterdam [PDF]

, 2010
In this study, an assessment of the intensity of the urban heat island (UHI) in Rotterdam was carried out using an innovative mobile bio-meteorological measuring platform mounted on a cargo bicycle.
Holtslag, A.A.M., Steeneveld, G.J., Elbers, J.A., Moors, E.J., Heusinkveld, B.G., Hove, L.W.A., van, Jacobs, C.M.J.   +6 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source