Results 91 to 100 of about 49,903 (309)
Pulmonary capillary permeability to HRP in dogs: a physiological and morphological study
, 1977 Pulmonary capillary permeability was studied in 10 normal anesthetized dogs using horseradish peroxidase (HRP) as tracer. Physiological studies involved measurement of left ventricular, pulmonary arterial, and wedge pressures, and of right lymphatic ...
J. C. Hogg, S. Inoue, R. P. Michel
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Frontiers in Physiology, 2017 Red blood cell (RBC) deformability has a significant impact on microcirculation by affecting cell dynamics. Despite previous studies that have demonstrated the margination of rigid cells and particles in vitro, little information is available on the in ...
Bumseok Namgung +8 more
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Plasma-soluble marker for intraorgan regional flows
, 1983 Measurement of regional plasma flow is needed to quantitate the delivery of substrates and drugs to cells. For estimating regional plasma flows an ideal deposition marker should be 100% extracted during transorgan passage and retained until local tissue
S. E. Little, J. B. Bassingthwaighte
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Biology and Mechanics of Blood Flows
, 2008 Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part I of this two-volume sequence, Biology, addresses the
Thiriet, Marc
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Microscopic images processing for the wood structure analysis
Журнал Белорусского государственного университета: Математика, информатика, 2018 An algorithm for analysis of wood fibers displacement and changes of the wood structure during deformation is proposed. This algorithm is intended for determination of changes in the structure of plant cells under stress and for study the mechanical ...
Olga V. Nedzvedz +3 more
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Oscillating shear index, wall shear stress and low density lipoprotein accumulation in human RCAs
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Soulis, JV +4 more
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