Results 91 to 100 of about 50,016 (309)
Flow field characterisation of aggregating human blood in bifurcating microchannels [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Balabani, S +4 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigation of physiological pulsatile flow in a model arterial stenosis using large-eddy and direct numerical simulations [PDF]
, 2012 Physiologicalpulsatileflow in a 3D model of arterialstenosis is investigated by using largeeddysimulation (LES) technique. The computational domain chosen is a simple channel with a biological type stenosis formed eccentrically on the top wall.
Molla, M.M. +3 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Regional blood flows in salt loading hypertension in the dog [PDF]
, 1981 An intravenous infusion of isotonic sodium chloride, 196 ml/kg per day, was administered for several days to eight dogs with their renal mass reduced.
J. F. Liard
core +1 more source
A novel tube law analysis under anisotropic external load
Scientific ReportsMathematical and physical modeling of flows in collapsible pipes often relates the flow area to the difference between the internal and the external pressures (i.e. the transmural pressure).
Lorenzo Lotti +3 more
doaj +1 more source
Methods and Protocols, 2020 Parallel plate flow chambers are widely used to expose cultured cells to physiological flows for the investigation of a variety of diseases. These applications usually involve the generation of continuous and steady fluid flow over cell monolayers for ...
Samar Shurbaji +4 more
doaj +1 more source
Flow of Physiological Fluids in Microchannels: The Sedimentation Effect [PDF]
, 2010 Microfluidic devices are becoming one of the most promising new tools for diagnostic applications and treatment of several chronic diseases. Hence, it is increasingly important to investigate the rheological behaviour of physiological fluids in microchannels.
Garcia, Valdemar +3 more
openaire +4 more sources
THE PHYSIOLOGICAL VARIATIONS IN RESISTANCE TO BILE FLOW TO THE INTESTINE [PDF]
Journal of Experimental Medicine, 1926 Under specially controlled conditions in the healthy unanesthetized dog we have measured the resistance offered to the flow of bile through the lower common duct. The average resistance 4 to 12 hours after a feeding was found to correspond to the pressure of a column of bile 100 to 120 mm. in height.
R, Elman, P D, McMaster
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source