Results 81 to 90 of about 50,016 (309)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Dynamic model of the lactating dairy cow metabolism

open access: yesAnimal, 2007
The whole-animal model described in this paper is intended to be a research model with an intermediary structure between sophisticated and simple cow models.
O. Martin, D. Sauvant
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Modeling and simulation of the mixing process of fluids in microchannels promoted by acoustic streaming [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Lanceros-Mendez, S   +4 more
core  

Total and regional blood flows in vascularized skeletal muscle grafts in rabbits [PDF]

open access: yes, 1988
The transplantation of whole skeletal muscles is a common clinical procedure. Although atypical blood flows have been reported in small free muscle grafts, the blood flow of large neurovascular-intact (NVI) and neurovascular-anastomosed (NVA) grafts ...
H. W. Burton   +4 more
core   +1 more source

In situ-Like Aerosol Inhalation Exposure for Cytotoxicity Assessment Using Airway-on-Chips Platforms

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Lung exposure to inhaled particulate matter (PM) is known to injure the airway epithelium via inflammation, a phenomenon linked to increased levels of global morbidity and mortality.
Shani Elias-Kirma   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Analysis and control of resonant cavity flows [PDF]

open access: yes, 2013
Recently, the trend for the internalisation of stores within an aircraft fuselage has led to a renewed interest in the field of cavity aero-acoustics.
Roberts, David
core  

Regional blood flows in the goat latissimus dorsi muscle before and after chronic stimulation [PDF]

open access: yes, 1996
Klabunde, Richard E., William A. Anderson, Marius Locke, Sigrid E. Ianuzzo, and C. David Ianuzzo. Regional blood flows in the goat latissimus dorsi muscle before and after chronic stimulation. J. Appl. Physiol.
C. David Ianuzzo   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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