Results 81 to 90 of about 50,016 (309)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Dynamic model of the lactating dairy cow metabolism
The whole-animal model described in this paper is intended to be a research model with an intermediary structure between sophisticated and simple cow models.
O. Martin, D. Sauvant
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Modeling and simulation of the mixing process of fluids in microchannels promoted by acoustic streaming [PDF]
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Lanceros-Mendez, S +4 more
core
Total and regional blood flows in vascularized skeletal muscle grafts in rabbits [PDF]
The transplantation of whole skeletal muscles is a common clinical procedure. Although atypical blood flows have been reported in small free muscle grafts, the blood flow of large neurovascular-intact (NVI) and neurovascular-anastomosed (NVA) grafts ...
H. W. Burton +4 more
core +1 more source
In situ-Like Aerosol Inhalation Exposure for Cytotoxicity Assessment Using Airway-on-Chips Platforms
Lung exposure to inhaled particulate matter (PM) is known to injure the airway epithelium via inflammation, a phenomenon linked to increased levels of global morbidity and mortality.
Shani Elias-Kirma +5 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Analysis and control of resonant cavity flows [PDF]
Recently, the trend for the internalisation of stores within an aircraft fuselage has led to a renewed interest in the field of cavity aero-acoustics.
Roberts, David
core
Regional blood flows in the goat latissimus dorsi muscle before and after chronic stimulation [PDF]
Klabunde, Richard E., William A. Anderson, Marius Locke, Sigrid E. Ianuzzo, and C. David Ianuzzo. Regional blood flows in the goat latissimus dorsi muscle before and after chronic stimulation. J. Appl. Physiol.
C. David Ianuzzo +4 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

