Effect of pulsatile flow perfusion on decellularization [PDF]
BioMedical Engineering OnLine, 2018 Background Decellularized animal organs have been used as scaffolds for tissue engineering. To make a properly functioning scaffolds, the extracellular matrix (ECM) components must be preserved after decellularization.
Sung Min Park +3 more
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Nonlinear hydrodynamic instability and turbulence in pulsatile flow. [PDF]
Proc Natl Acad Sci U S A, 2020 Significance The inner lining of blood vessels, the endothelium, is shear sensitive. Fluctuating shear stresses and disordered flow are responsible for cellular dysfunction, leading to the development of atherosclerotic lesions.
Xu D +6 more
europepmc +3 more sources
Critical Care, 2019 Background Systemic blood flow in patients on extracorporeal assist devices is frequently not or only minimally pulsatile. Loss of pulsatile brain perfusion, however, has been implicated in neurological complications.
Cecilia Maria Veraar +9 more
doaj +2 more sources
Electrocardiogram-synchronized pulsatile extracorporeal life support preserves left ventricular function and coronary flow in a porcine model of cardiogenic shock. [PDF]
PLoS ONE, 2018 Veno-arterial extracorporeal life support (ECLS) is increasingly being used to treat rapidly progressing or severe cardiogenic shock. However, it has been repeatedly shown that increased afterload associated with ECLS significantly diminishes left ...
Petr Ostadal +14 more
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Effects of pulsatile flow on postoperative recovery in adult cardiac surgery with cardiopulmonary bypass: A systematic review and meta-analysis of randomized controlled trials [PDF]
HeliyonBackground: The role of pulsatile versus non-pulsatile flow during cardiopulmonary bypass (CPB) is still in debate. This systematic review aimed to comprehensively assess the impact of pulsatile versus non-pulsatile flow on patients’ recovery.
Weidong Yan +6 more
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Generation of Pulsatile Flow using Clinical Continuous Flow Pumps [PDF]
JHLT OpenBackground: With the increasing use of mechanical circulatory support for long-term augmentation of cardiopulmonary function, the need for safer devices is apparent.
Joav Birjiniuk +4 more
doaj +2 more sources
Numerical simulation of spatiotemporal red blood cell aggregation under sinusoidal pulsatile flow [PDF]
Scientific Reports, 2021 Previous studies on red blood cell (RBC) aggregation have elucidated the inverse relationship between shear rate and RBC aggregation under Poiseuille flow.
Cheong-Ah Lee, Dong-Guk Paeng
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A Multi-Domain Simulation Study of a Pulsatile-Flow Pump Device for Heart Failure With Preserved Ejection Fraction [PDF]
Frontiers in Physiology, 2022 Mechanical circulatory support (MCS) devices are currently under development to improve the physiology and hemodynamics of patients with heart failure with preserved ejection fraction (HFpEF).
Caglar Ozturk +4 more
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Aortic wave dynamics and its influence on left ventricular workload. [PDF]
PLoS ONE, 2011 The pumping mechanism of the heart is pulsatile, so the heart generates pulsatile flow that enters into the compliant aorta in the form of pressure and flow waves.
Niema M Pahlevan, Morteza Gharib
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Large–Eddy simulation of pulsatile blood flow [PDF]
Medical Engineering and Physics, 2009 Large-Eddy simulation (LES) is performed to study pulsatile blood flow through a 3D model of arterial stenosis. The model is chosen as a simple channel with a biological type stenosis formed on the top wall.
Manosh C Paul +2 more
exaly +3 more sources