Results 131 to 140 of about 818,500 (292)
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Psychological and physiological integration in developing futsal passing skills among students
Background and Study Aim. Passing accuracy in futsal depends on both physical abilities and psychological readiness, which together determine the effectiveness of decision-making and execution during play.
Didik Purwanto +3 more
doaj +1 more source
Physiological Integration Increases Sexual Reproductive Performance of the Rhizomatous Grass Hierochloe glabra. [PDF]
Guo J, Li H, Yang Y.
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Correlation Differences in Heartbeat Fluctuations During Rest and Exercise
We study the heartbeat activity of healthy individuals at rest and during exercise. We focus on correlation properties of the intervals formed by successive peaks in the pulse wave and find significant scaling differences between rest and exercise.
A. Bunde +21 more
core +1 more source
Neuronal Pathways and Synaptic Connexions in the Abdominal Cord of the Crayfish [PDF]
1. An investigation has been made into the function and distribution of nerve fibres in the abdominal ganglion chain and its roots in the crayfish, Procambarus clarkii, by leading off action potentials from small prepared bundles following sensory ...
Hughes, G. M., Wiersma, C. A. G.
core +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Editorial: Data integration and physiological modelling
Yasha Hasija
doaj +1 more source

