Results 141 to 150 of about 4,628,531 (299)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Physiological Integration Increases Sexual Reproductive Performance of the Rhizomatous Grass Hierochloe glabra. [PDF]

Plants (Basel), 2020
Guo J, Li H, Yang Y.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Editorial: Data integration and physiological modelling

Frontiers in Physiology, 2023
Yasha Hasija
doaj   +1 more source

ROS 4 healthcare: a framework for physiological human sensing for social, assistive, rehabilitation, and medical robotics

Frontiers in Robotics and AI
The pervasive integration of robots into daily life necessitates advanced human-robot interaction (HRI) capabilities, particularly the accurate understanding of human physiological and cognitive states.
Ricardo Javier Manríquez-Cisterna, Pranjal Mishra, Pranjal Mishra, Jorge Peña-Queralta, Monica Perez-Serrano, Monica Perez-Serrano, Spyridon Garyfallidis, Spyridon Garyfallidis, Lucas Kupper, Lucas Kupper, Mehdi Ejtehadi, Mehdi Ejtehadi, Alexander Breuss, Ankit A. Ravankar, Jose Victorio Salazar Luces, Robert Riener, Robert Riener, Yasuhisa Hirata, Diego Paez-Granados, Diego Paez-Granados   +19 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Integration of Ensemble and Evolutionary Machine Learning Algorithms for Monitoring Diver Behavior Using Physiological Signals

, 2019
Integration of Ensemble and Evolutionary Machine Learning Algorithms for Monitoring Diver Behavior Using Physiological ...
Afsaneh Koohestani (13056750), M Abdar (14452800), S Nahavandi (13392411), Abbas Khosravi (13078944), A Koohestani (13539931)   +4 more
core  

Shorterm fitness benefits of physiological integration in the clonal herb hydrocotyle peduncularis

, 2015
We test whether physiological integration enhances the short-term fitness of the clonal herb Hydrocotyle peduncularis (Apiaceae, R. Brown ex A. Richards) subjected to spatial variation in water availability.
Peterson, Vicki, Chesson, Peter
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source