Results 171 to 180 of about 1,856,828 (312)

Seed vigor and initial growth of corn crop

Journal of Seed Science
Seed vigor is a characteristic that determines potential for fast and uniform seedling emergence and establishment of crops. Such characteristic defines crop initial growth what could have direct and indirect effects on capacity of plants in capturing ...
Vitor Henrique Vaz Mondo, Silvio Moure Cicero, Durval Dourado-Neto, Túlio Lourenço Pupim, Marcos Altomani Neves Dias   +4 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Physiological measurement techniques in virtual tourism research: three caveats for future studies

Research on virtual tourism is receiving substantial scholarly attention. Existing studies on virtual tourism tend to apply self-report methods to assess user experiences, overlooking the potential of physiological measurement techniques.
Kralj, Anna, Nhan, Minh, Liu, Biqiang, Moyle, Brent   +3 more
core   +1 more source

Action of defense activator and foliar fungicide on the control of Asiatic rust and on yield and quality of soybean seeds

Journal of Seed Science
The objective of this study was to evaluate the influence of fungicide application (PrioriXtra®, azoxystrobin + ciproconazole) and defense activator (Bion®, acibenzolar-S-methyl) on the control of Asiatic rust (Phakopsora pachyrhizi), as well as the ...
Bruno Oliveira Carvalho, João Almir Oliveira, Everson Reis Carvalho, Vinícius de Andrade, Thaís Francielle Ferreira, Leandro Vilela Reis   +5 more
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A comparative study of the nutritional and physiological potential of Xuta (edible <i>Jatropha curcas</i> L.) protein: Insights into its digestibility and effects on the intestinal barrier. [PDF]

Curr Res Food Sci
Grünwald M, Adrar N, Francis G, Rugen N, Döring M, Braun HP, Esatbeyoglu T.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Systemic neurophysiological entrainment to behaviorally relevant rhythmic stimuli

Physiological oscillations, such as those involved in brain activity, heartbeat, and respiration, display inherent rhythmicity across various timescales.
Vázquez Morejón, Antonio José, Gómez González, Carlos María, Muñoz Burbano, Vanesa, Muñoz Caracuel, Manuel, Ruiz Martínez, Francisco Javier   +4 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source