Artificial Intelligence Enabled Diagnostics Using Photoplethysmography (PPG): Beyond SpO<sub>2</sub> and Heart Rate. [PDF]
Joshi DD +35 more
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Mechanistic Pathways Underlying Breastfeeding Challenges Following Cesarean Delivery: A Systematic Review. [PDF]
Basrowi RW +5 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
The Tol-Pal System Promotes Pseudoiodinine Production by Enhancing Bacterial Growth in <i>Pseudomonas mosselii</i>. [PDF]
Yang R +7 more
europepmc +1 more source
Illuminating Potential Harms of the Physiologic Futility Standard
Julia K. Axelrod +4 more
openaire +2 more sources
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Targeting NF-κB Signaling in Preterm Labor: Molecular Mechanisms and Therapeutic Perspectives. [PDF]
Marynowski M +4 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Mechanism-based nutritional strategies for performance and recovery in soccer players: a qualitative research synthesis. [PDF]
Azizi Ammarati AH +2 more
europepmc +1 more source

