Results 241 to 250 of about 11,245,204 (305)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

An accessible path to nature: piloting virtual nature interventions among adults with disabilities by examining heart rate variability. [PDF]

Front Psychol
Gorr ND, Ochi A, Niemi M, Huotilainen M.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

<i>Arabidopsis</i> bZIP68 Modulates Flowering Time Potentially with Chromatin and Stress-Responsive Regulators. [PDF]

Biology (Basel)
Park C, Geem KR, Choi BY, Kim J.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Editorial: Animal nutrition and immunometabolism: from basic mechanisms to sustainable production. [PDF]

Front Vet Sci
Yuan J, Cao P, Liu P, Gao X, Gu X, Vargas-Bello-Pérez E, Zhuang Y, Hu G.   +7 more
europepmc   +1 more source

Contribution of Aerobic Physiological Variables to 500 m Sprint Kayak Performance in National-Level Athletes: A Hierarchical Regression Analysis. [PDF]

Sports (Basel)
Papandreou A, Paradisis G, Philippou A, Zacharogiannis E.   +3 more
europepmc   +1 more source

Social Physiology: Human homeostasis is more efficient in social proximity. [PDF]

Sci Adv
Masalha M, Cohen M, Aloni M, Toledo E, Stahl E, Shachar D, Eliav O, Fuchs S, Atzil S.   +8 more
europepmc   +1 more source

Plant electrophysiological responses to drought and their association with live fuel moisture and flammability in <i>Salvia rosmarinus</i>. [PDF]

Plant Signal Behav
Fuente D, Zapata R, Martínez-Heras E, Raigón MD, Oliver-Villanueva JV.   +4 more
europepmc   +1 more source