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Adrenomedullin: Potential in physiology and pathophysiology

Life Sciences, 2000
Adrenomedullin (ADM), a 52-amino acid ringed-structure peptide with C-terminal amidation, was originally isolated from human pheochromocytoma. ADM mediates vasodilatory and natriuretic properties through the second messenger cyclic adenosine 3',5'-monophosphate (cAMP), nitric oxide and the renal prostaglandin system.
M, Jougasaki, J C, Burnett
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Physiological mechanisms underlying long-term potentiation

Trends in Neurosciences, 1988
Abstract In 1949, D. O. Hebb suggested a synaptic modification for learning and memory that occurs as a consequence of coincidence between pre- and post-synaptic activity 1 . This concept has gained wide acceptance and is often used, in its original or modified form, in neuronal net models dealing with learning and memory 2 .
B, Gustafsson, H, Wigström
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