Results 71 to 80 of about 1,656,577 (267)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Adequação do teste de condutividade elétrica para sementes de Pisum sativum subsp. Arvense Suitability of electrical conductivity test for seeds of Pisum sativum subsp. Arvense

Ciência Rural, 2011
A qualidade da semente na produção agrícola é um dos principais fatores a ser considerado na implantação da cultura, de forma que se torna importante a obtenção de informações sobre a germinação e o vigor das sementes, além da necessidade de avaliá-los ...
Carla Gomes Machado, Cibele Chalita Martins, Denise Garcia de Santana, Simério Carlos Silva Cruz, Silvia Sanielle Costa de Oliveira   +4 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Optimizing Basil Seed Vigor Evaluations: An Automatic Approach Using Computer Vision-Based Technique

Horticulturae
The short cultivation cycle and high essential oil content of basil plants render them a valuable raw material source for diverse industries. However, large-scale production is hindered by the lack of specific protocols to assess seed vigor; thus, a ...
Júlio César Altizani-Júnior, Silvio Moure Cicero, Cristina Batista de Lima, Rafael Mateus Alves, Francisco Guilhien Gomes-Junior   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Physiological potential and evolutionary trajectories of syntrophic sulfate-reducing bacterial partners of anaerobic methanotrophic archaea. [PDF]

PLoS Biol, 2023
Murali R, Yu H, Speth DR, Wu F, Metcalfe KS, Crémière A, Laso-Pèrez R, Malmstrom RR, Goudeau D, Woyke T, Hatzenpichler R, Chadwick GL, Connon SA, Orphan VJ.   +13 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Physiological maturity of Physalis angulata L. seeds

Revista Ciência Agronômica, 2019
Determination of seed physiological maturity allows predicting the most appropriate time for harvest, aiming to obtain seeds with high physiological potential. Physalis angulata (Solanaceae) has pharmacological and agro-industrial potential, but there is
Willen Ramos Santiago, Juliana Simões Nobre Gama, Salvador Barros Torres, Gianluigi Bacchetta   +3 more
doaj   +1 more source

The physiological potential of anammox bacteria as revealed by their core genome structure. [PDF]

DNA Res, 2021
Okubo T, Toyoda A, Fukuhara K, Uchiyama I, Harigaya Y, Kuroiwa M, Suzuki T, Murakami Y, Suwa Y, Takami H.   +9 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source