Results 71 to 80 of about 9,116,740 (314)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Evaluation of physiological and morphological basis for drought resistance in maize and sorghum [PDF]
, 2004 Includes bibliographical references (leaves 145-171).Drought stress is often the most limiting factor to maize and sorghum production in the semi-arid areas.
Takele, Abuhay
core +1 more source
Osmotic stress on genetically transformed tobacco plant seeds
Journal of Seed Science: Salinity and water deficit limit the productivity of several crops; thus, studies related to the genetic transformation of seeds in a model plant, such as tobacco, can be an alternative to minimize negative impacts caused by environmental conditions ...
Michele Trombin-Souza +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Ciência Rural, 2005 O experimento teve como objetivo avaliar o efeito de combinações da distribuição das sementes de soja de alto e baixo vigor ao longo da linha de semeadura, sobre o comportamento individual das plantas resultantes e o desempenho geral das comunidades ...
Eliane Maria Kolchinski +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Identification of physiological analysis parameters associated with coffee beverage quality.
, 2020 The demand for high-quality coffee among consumers has generated a great deal of interest among producers in serving this market. Parameters for physiological analyses that can be associated with aspects of sensory analyses of coffee can ensure more ...
FREITAS, M. N. de +4 more
core +1 more source
Pesquisa Agropecuária Brasileira, 2013 O objetivo deste trabalho foi avaliar metodologias para realização do teste de tetrazólio, na avaliação da viabilidade e do vigor de sementes de girassol, e estabelecer classes de qualidade para interpretação do teste.
Rosemeire Carvalho da Silva +3 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source