Results 81 to 90 of about 9,116,740 (314)

Perceptual video quality evaluation by means of physiological signals [PDF]

open access: yes, 2017
The proliferation of multimedia technology and its wide adoption by users has created the need for more effective metrics for Quality of Experience (QoE).
Ramzan, Naeem   +9 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Quality Improvement Division Operational Plan 2016 [PDF]

open access: yes, 2016
This is the second Operational Plan for the Quality Improvement Division (QID) since its establishment in 2015 and it builds on the work in 2015 to enable the HSE develop and implement a quality improvement agenda and capability across all levels of the ...
Quality Improvement Division
core  

Effect of Wounding Intensity on Edible Quality by Regulating Physiological and ROS Metabolism in Fresh-Cut Pumpkins

open access: yes, 2023
Fresh-cut pumpkin is favored by consumers for its environmental protection, safety, and convenience at home and abroad. To investigate the effect of different wounding intensities (piece, strip and slice, corresponding to 1.90, 3.53 and 6.29 m2 kg&minus ...
Yi Wang   +3 more
core   +1 more source

Improved assessment of wheat seeds vigor Melhor avaliação do vigor de sementes de trigo

open access: yesCiência e Agrotecnologia, 2012
The tetrazolium test is widely used for seed vigor assessment of various plant species. For wheat, however, there is no methodology specifically recommended.
Tereza Cristina de Carvalho   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ecofisiologia da germinação de sementes de Aspidosperma cylindrocarpon Müll. Arg.(peroba-poca) Ecophysiology of seed germination in Aspidosperma cylindrocarpon Müll. Arg. (peroba-poca). [PDF]

open access: yesRevista do Instituto Florestal, 2011
Sementes de Aspidosperma cylindrocarpon foram colocadas para germinar, na temperatura de 20-25 oC sobre vermiculita, umedecida com 30, 60 e 90 mL de água destilada, na ausência de luminosidade e sob luz branca, vermelha e vermelha extrema com o objetivo ...
Antonio da SILVA   +3 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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