Results 131 to 140 of about 11,227,971 (354)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Comparative Transcriptomics Reveals Potential Regulatory Mechanisms Underlying Changes in Antioxidant, Anti-Inflammatory, and Other Immune Functions Induced by Bellamya purificata Polysaccharides in Cherax quadricarinatus

Antioxidants
This study investigated the potential effects of Bellamya purificata polysaccharide (BPP) supplementation in feed on Cherax quadricarinatus, aiming to elucidate its impact on immune function and the underlying regulatory mechanisms.
Chang Yuan, Huizan Yang, Xianhui Pan, Yong Lin, Kangqi Zhou, Feng Lin, Wenjian Chen, Yusen Li, Yaoquan Han, Hui Wei, Caiguang Wang, Liangliang Huang, Dapeng Wang   +12 more
doaj   +1 more source

Role of stress in progression of Migraine

International Journal of Endorsing Health Science Research, 2014
The mental and physiological stresses can be an important trigger of migraines & headaches. These strains act to enhance the progression of migraine that could be psychological, physiological stress, Environmental stress or Chemical stress.
Shamoon Noushad, Sadaf Ahmed, Huma Khalid, Rida Nasir, Ikram Tunio, Shaikh Tahir   +5 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Stress System – Organization, Physiology and Immunoregulation

Neuroimmunomodulation, 2006
Stress is defined as a state of threatened homeostasis. The principal effectors of the stress system include corticotropin-releasing hormone, arginine vasopressin, the glucocorticoids, and the catecholamines norepinephrine and epinephrine. Activation of the stress system leads to adaptive behavioral and physical changes.
Elenkov, I.J., Chrousos, G.P.
openaire   +3 more sources

Association of Proteomics Changes with Al-Sensitive Root Zones in Switchgrass

Proteomes, 2018
In this paper, we report on aluminum (Al)-induced root proteomic changes in switchgrass. After growth in a hydroponic culture system supplemented with 400 μM of Al, plants began to show signs of physiological stress such as a reduction in photosynthetic ...
Mahesh Rangu, Zhujia Ye, Sarabjit Bhatti, Suping Zhou, Yong Yang, Tara Fish, Theodore W. Thannhauser   +6 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Standard methods for estimating mechanical work in high-intensity functional training: an exercise compendium

Frontiers in Sports and Active Living
High-intensity functional training (HIFT) presents unique challenges for quantifying training load due to the variability of exercises, movement standards, and workout structures.
Gerald T. Mangine, Gerald T. Mangine, Caralynn Doese, Adam R. Jajtner   +3 more
doaj   +1 more source

The acute physiological stress response to driving: A systematic review

PLoS ONE, 2017
Background The experience of driving has been suggested to be detrimental to health. One hypothesis is that each exposure elicits an acute stress response, and that repeated exposures may act as a chronic stressor.
Michael Antoun, K. Edwards, J. Sweeting, D. Ding   +3 more
semanticscholar   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source