Results 131 to 140 of about 152,759 (266)

Proteinuria and Significant Dehydration in a Short-Steep Triathlon: Preliminary Observational Report

Physiologia
Background/Objectives: Endurance triathlons impose substantial physiological stress, yet the effects of short-course formats remain relatively unexplored.
Daniel Rojas-Valverde, Cindy Castro, Diego A. Bonilla, Luis A. Cardozo, Carlos D. Gómez-Carmona   +4 more
doaj   +1 more source

Evaluation of physiological and morphological basis for drought resistance in maize and sorghum

, 2004
Includes bibliographical references (leaves 145-171).Drought stress is often the most limiting factor to maize and sorghum production in the semi-arid areas.
Takele, Abuhay
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Effect of post-weaning management practices on physiological and immunological responses of weaned beef calves [PDF]

, 2011
peer-reviewedThe objectives were: i) to investigate the physiological and immunological responses of previously grazed, abruptly weaned beef calves that were then either housed (H) and offered a diet of grass silage ad libitum plus concentrate or ...
Lynch, E.M., McGee, Mark, McGee, M., Lynch, Eilish M, Doyle, Sean, Earley, Bernadette, Earley, B.   +6 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The physiological and behavioural responses of sheep exposed to heat load within intensive sheep industries

, 2006
The live export and feedlotting industries are the major intensive sheep industries in Australia. During live shipment, sheep are exposed to prolonged periods of high heat and humidity, with little relief for several days, while environmental conditions ...
Stockman, Catherine Ann
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Physiological and behavioural responses to fear and discomfort in dogs and goats [PDF]

, 2010
In this thesis, behavioural and physiological methods were combined to better understand reactions to fearful situations in dogs and separation in goats. Fear of gunshots is common in dogs, but also other fears, such as fear of walking on certain floors.
Winblad von Walter, Louise
core