Results 141 to 150 of about 11,227,971 (354)

The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development

Journal of Cell Science, 2017
IRE1 mediates the unfolded protein response (UPR) in part by regulating XBP1 mRNA splicing in response to endoplasmic reticulum (ER) stress. In cultured metazoan cells, IRE1 also exhibits XBP1-independent biochemical activities.
Huai-Wei Huang, Xiaomei Zeng, T. Rhim, D. Ron, H. Ryoo   +4 more
semanticscholar   +1 more source

Evaluation of Peanut Physiological Responses to Heat and Drought Stress Across Growth Chamber and Field Environments [PDF]

Heat-exacerbated drought stress is becoming increasingly common in crop production systems, including peanuts, yet limited information exists on how peanut cultivars respond to this combined stress.
David C. Haak, Ranadheer Reddy Vennam, Balota, Maria, Maria Balota, Haak, David C., Beard, Keely M., Vennam, Ranadheer Reddy, Keely M. Beard   +7 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Predicting task performance in robot-assisted surgery using physiological stress and subjective workload: a case study with interpretable machine learning

Frontiers in Human Neuroscience
Robot-assisted surgery (RAS) enhances surgical precision and extends surgeons’ capabilities. However, its effects on the cognitive and physical states of surgeons remain poorly understood.
Kaiqi Wei, Chika Kimura, Megumi Shimura, Yoshihiro Shimomura, Xue Zhao, Takaaki Tamura, Shinichi Sakamoto   +6 more
doaj   +1 more source

Potential Polyunsaturated Aldehydes in the Strait of Gibraltar under Two Tidal Regimes

Marine Drugs, 2014
Diatoms, a major component of the large-sized phytoplankton, are able to produce and release polyunsaturated aldehydes after cell disruption (potential PUAs or pPUA).
Soledad Morillo-García, Nerea Valcárcel-Pérez, Andrés Cózar, María J. Ortega, Diego Macías, Eduardo Ramírez-Romero, Carlos M. García, Fidel Echevarría, Ana Bartual   +8 more
doaj   +1 more source

The biopsychosocial model of stress in adolescence: self-awareness of performance versus stress reactivity [PDF]

, 2017
Extensive research among adults supports the biopsychosocial (BPS) model of challenge and threat, which describes relationships among stress appraisals, physiological stress reactivity, and performance; however, no previous studies have examined these ...
Nock, Matthew, Rith-Najarian, Leslie R., Sheridan, Margaret, McLaughlin, Katie   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of pre-competition weight loss on onautonomic regulation and functional state qualified powerlifters

Слобожанський науково-спортивний вісник
Background and purpose of the study.Pre-competition weight loss is a common practice among powerlifters to compete in lower weight categories. However its impact on autonomic regulation and functional status in female powerlifters remains poorly ...
Oleh Olkhovyi, Oleksandr Tykhorskyi, Natalya Didyuk, Viktor Savchenko, Serhii Babenko, Vyacheslav Romanenko, Vladimir Potop   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source