Results 41 to 50 of about 939,492 (295)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Stress Physiology of Lactic Acid Bacteria [PDF]

Microbiology and Molecular Biology Reviews, 2016
SUMMARY Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms. The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by the technological implications of LAB robustness in the food industry.
Papadimitriou, Konstantinos, Alegría, Ángel, Bron, Peter A., De Angelis, Maria, Gobbetti, Marco, Kleerebezem, Michiel, Lemos, José A., Linares, Daniel M., Ross, Paul, Stanton, Catherine, Turroni, Francesca, Van Sinderen, Douwe, Varmanen, Pekka, Ventura, Marco, Zúñiga, Manuel, Tsakalidou, Effie, Kok, Jan   +16 more
openaire   +4 more sources

Under Pressure? A Study of Heart Rate and Heart-Rate Variability Using SmarTerp

Hermes, 2023
The results of a quasi-experimental, intra-subject study are reported on the effects of the use of SmarTerp on physiological stress levels of twelve second-year students of the MA in Interpreting at the University of Bologna during a simultaneous ...
Christian, Nicoletta Spinolo, Ricardo Muñoz Martín   +2 more
doaj  

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The effect of fish density and tank size on the behavior of adult zebrafish: A systematic analysis

Frontiers in Behavioral Neuroscience, 2022
The zebrafish has been employed in several fields of biology due to its translational relevance and its simplicity and ease of maintenance. As a result, zebrafish are kept in thousands of laboratories around the world.
Stephanie Shishis, Benjamin Tsang, Benjamin Tsang, Robert Gerlai, Robert Gerlai   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Physiological Stress Mediated by Corticosterone Administration Alters Intestinal Bacterial Communities and Increases the Relative Abundance of Clostridium perfringens in the Small Intestine of Chickens

Microorganisms, 2020
A model of physiological stress mediated by the administration of corticosterone (CORT) was used to investigate the impact of stress on the intestinal microbiota of chickens.
Sarah J. M. Zaytsoff, Richard R. E. Uwiera, G. Douglas Inglis   +2 more
doaj   +1 more source

Effects of Positive Reinforcement Training and Novel Object Exposure on Salivary Cortisol Levels under Consideration of Individual Variation in Captive African Elephants (Loxodonta africana)

Animals, 2021
Dealing with potential stress in species that have high husbandry requirements, such as elephants, is a challenge for zoos. The objective of the present study was to determine whether positive reinforcement training (PRT) and exposure to a novel object ...
Susan Hambrecht, Ann-Kathrin Oerke, Michael Heistermann, Johannes Hartig, Paul W. Dierkes   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Impact of 24 h shifts on urinary catecholamine in emergency physicians: a cross-over randomized trial

Scientific Reports
24-h shift (24 hS) exposed emergency physicians to a higher stress level than 14-h night shift (14 hS), with an impact spreading on several days. Catecholamines are supposed to be chronic stress biomarker.
Frédéric Dutheil, Alicia Fournier, Christophe Perrier, Damien Richard, Marion Trousselard, George Mnatzaganian, Julien S. Baker, Reza Bagheri, Martial Mermillod, Maelys Clinchamps, Jeannot Schmidt, Jean-Baptiste Bouillon-Minois   +11 more
doaj   +1 more source