Results 131 to 140 of about 1,308,964 (265)

ON THE MECHANISMS OF ACUPUNCTURE ANALGESIA

针刺研究, 1984
Han Jisheng Department of physiology
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

THE ROLE OF NUCLEUS RAPHE MAGNUS (NRM) IN ACUPUNCTURE ANTI-VISCERALGIA

针刺研究, 1981
Zhu Lixia Qiao Hueli~ Zhang Changchen~ Li Lina Department of Physiology, Beijing Agriculture UniversityDepatrment of Physiology, Zunyi Medical College.   +2 more
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

THE ROLE OF NUCLEUS RAPHE MAGNUS IN ACUPUNCTURE ANALGESIA AND THE CONTROL OF SOME HIGHER ANALGESIC STRUCTURE ON IT

针刺研究, 1984
Liu Xiang The First Department of Physiology
doaj  

Radial Wall Strain and the Stepwise Integration of Physiology and Vulnerability in Revascularization Decision Making. [PDF]

JACC Asia
Skalidis I, Wenaweser P, Meier P, Cook S, Togni M.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Reversible constrictive physiology caused by a tuberculous pericardial mass. [PDF]

Eur Heart J Case Rep
Bhardwaj A, Vasudev I, Vasudev R, Egambaram D.   +3 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

EFFECT OF NAIOXONE ON NEUCLEUS RAPHE MAGNUS (NRM) STIMULATION-PRODUCED ANALGESIA

针刺研究, 1981
Zhu Lixia Qiao Huili~ Zhang Zhangchen~ Li Lina Department of Physiology, Beijing Agriculture University.Department of Physiology, Zunyi Medical College.   +2 more
doaj