Results 151 to 160 of about 1,799,621 (293)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Physiology CBCS-General Question Paper,2019

open access: yes, 2019
Physiology CBCS-General Question ...
Vidyasagar University
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

THE ROLE OF NUCLEUS RAPHE MAGNUS (NRM) IN ACUPUNCTURE ANTI-VISCERALGIA

open access: yes针刺研究, 1981
Zhu Lixia Qiao Hueli~ Zhang Changchen~ Li Lina Department of Physiology   +2 more
doaj   +2 more sources

Microvascular resistance reserve: insights into discordant resting and hyperemic epicardial coronary physiology. [PDF]

open access: yesFront Cardiovasc Med
Babu A   +16 more
europepmc   +1 more source

Physiology CBCS-General Question Paper,2018

open access: yes, 2018
Physiology CBCS-General Question ...
Vidyasagar University
core  

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