Results 191 to 200 of about 1,799,621 (293)

Extracorporeal Life Support in ARDS: Lessons from Maternal-Fetal Physiology. [PDF]

Adv Respir Med
Merola R, Battaglini D, Cho SM.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Correction: Neural correlates of spatial orientation in a territorial frog Allobates femoralis. [PDF]

J Comp Physiol A Neuroethol Sens Neural Behav Physiol
Pašukonis A, Fischer EK, O'Connell LA.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Alzheimer's disease research must connect vascular molecular phenotypes with physiology. [PDF]

PLoS Biol
Lewis TS, Wagner J, Neher JJ.
europepmc   +1 more source

Physiology in Perspective: Physiology is Alive and Well [PDF]

Physiology, 2018
openaire   +2 more sources

Human physiology in extreme environments /

Human Physiology in Extreme Environments is the one publication that offers how human biology and physiology is affected by extreme environments while highlighting technological innovations that allow us to adapt and regulate environments.
Opatz, Oliver,author., Stahn, Alexander Christoph,author., Gunga, Hanns-Christian,author., Steinach, Mathias,author.   +3 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Opening the black box of mechanical insufflation-exsufflation: bringing upper airway physiology to the bedside. [PDF]

ERJ Open Res
Crimi C, Impellizzeri P, Winck JC.
europepmc   +1 more source