Results 41 to 50 of about 1,827,107 (254)

The Physiology of Ventilation [PDF]

open access: yesRespiratory Care, 2014
The diffusion of gases brings the partial pressures of O2 and CO2 in blood and alveolar gas to an equilibrium at the pulmonary blood-gas barrier. Alveolar PCO2 (PACO2) dependson the balance between the amount of CO2 being added by pulmonary blood and the amount being eliminated by alveolar ventilation (V ̇ A).
Murias, G, Blanch, L, LUCANGELO, UMBERTO
openaire   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Impact of cell physiology and densities during oxidative axenic cultures of Yarrowia lipolytica on physico-chemical properties of broth [PDF]

open access: yes, 2013
Impact of cell physiology and densities during oxidative axenic cultures of Yarrowia lipolytica on physico-chemical properties of ...
Anne-Archard, Dominique   +4 more
core  

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Physiology [PDF]

open access: yesThe American Naturalist, 1908
n ...
openaire   +2 more sources

Crop and Livestock Insect Problems facing CGIAR Centres: A Proposal towards their Long-term Solution [PDF]

open access: yes, 1976
Proposal by ICIPE for cooperative programs with CGIAR centers on animal and plant pest control. Revised version of agenda document presented at TAC 11th Meeting.
International Centre of Insect Physiology and Ecology
core  

To germinate or not to germinate : a question of dormancy relief not germination stimulation [PDF]

open access: yes, 2012
A common understanding of the control of germination through dormancy is essential for effective communication between seed scientists whether they are ecologists, physiologists or molecular biologists. Vleeshouwers et al.
Batlla   +4 more
core   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Physiology of Astroglia [PDF]

open access: yesPhysiological Reviews, 2018
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters.
Verkhratsky, Alexei, Nedergaard, Maiken
openaire   +5 more sources

The Virtual Runner Learning Game [PDF]

open access: yes, 2013
A learning game has been developed which allows learners to study and learn about the significance of three important variables in human physiology (lactate, glycogen, and hydration) and their influence on sports performance during running.
Behringer, R   +6 more
core   +1 more source

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