Results 11 to 20 of about 77,054 (271)
APOE and Alzheimer’s Disease: From Lipid Transport to Physiopathology and Therapeutics
Frontiers in Neuroscience, 2021 Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations.
M. Husain, B. Laurent, M. Plourde
semanticscholar +1 more source
Extracellular vesicles, the emerging mirrors of brain physiopathology
International Journal on Biological Sciences, 2023 Extracellular vesicles are secreted by a wide variety of cells, and their primary functions include intercellular communication, immune responses, human reproduction, and synaptic plasticity.
A. Cano +11 more
semanticscholar +1 more source
Cutaneous Wound Healing: An Update from Physiopathology to Current Therapies
Life, 2021 The skin is the biggest organ of human body which acts as a protective barrier against deleterious agents. When this barrier is damaged, the organism promotes the healing process with several molecular and cellular mechanisms, in order to restore the ...
L. F. Gushiken +4 more
semanticscholar +1 more source
Vesicoureteral Reflux and Innate Immune System: Physiology, Physiopathology, and Clinical Aspects
Journal of Clinical Medicine, 2023 Vesicoureteral reflux represents one of the most concerning topics in pediatric nephrology due to its frequency, clinical expression with the potential to evolve into chronic kidney disease, and last but not least, its socio-economic implications.
Marius-Cosmin Colceriu +5 more
semanticscholar +1 more source
Post-COVID-19 acute sarcopenia: physiopathology and management
Aging Clinical and Experimental Research, 2021 In this review, we discuss the pathophysiologic and management aspects of acute sarcopenia in relation to SARS-CoV-2 infection. COVID-19 is as a multi-organ infectious disease characterized by a severe inflammatory and highly catabolic status ...
K. Piotrowicz +3 more
semanticscholar +1 more source
Interleukin-6 and pulmonary hypertension: from physiopathology to therapy
Frontiers in Immunology, 2023 Pulmonary hypertension (PH) is a progressive, pulmonary vascular disease with high morbidity and mortality. Unfortunately, the pathogenesis of PH is complex and remains unclear. Existing studies have suggested that inflammatory factors are key factors in
Wei-Jie Xu +7 more
semanticscholar +1 more source
Left Ventricular Remodeling after Myocardial Infarction: From Physiopathology to Treatment
Life, 2022 Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an incidence relatively high in developed countries and rapidly growing in developing countries.
Sabina Andreea Leancă +7 more
semanticscholar +1 more source
Antioxidants, 2022 The skin is constantly exposed to exogenous and endogenous sources of reactive oxygen species (ROS). An adequate balance between ROS levels and antioxidant defenses is necessary for the optimal cell and tissue functions, especially for the skin, since it
M. Emanuelli +8 more
semanticscholar +1 more source
Ferroptosis and its potential role in the physiopathology of Parkinson’s Disease
Progress in neurobiology, 2020 Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder characterised by motor impairments as well as non-motor symptoms. While dopamine-based therapies are effective in fighting the symptoms in the early stages of the disease, a ...
Laura Mahoney-Sánchez +5 more
semanticscholar +1 more source
Oxidative Medicine and Cellular Longevity, 2020 Oxidative stress (OS) has the ability to damage different molecules and cellular structures, altering the correct function of organs and systems. OS accumulates in the body by endogenous and exogenous mechanisms.
A. García-Sánchez +2 more
semanticscholar +1 more source