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FGF21 and Cardiac Physiopathology [PDF]
The heart is not traditionally considered either a target or a site of fibroblast growth factor-21 (FGF21) production. However, recent findings indicate that FGF21 can act as a cardiomyokine; that is, it is produced by cardiac cells at significant levels and acts in an autocrine manner on the heart itself. The heart is sensitive to the effects of FGF21,
Planavila Porta, Ana +2 more
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The physiopathology of lipoprotein a
Lipoprotein(a) (also called Lp(a)) is a lipoprotein subclass. Different studies have identified Lp(a) as a putative risk factor for atherosclerotic diseases such as coronary artery disease and stroke. The physiological role of Lp(a) in humans is still unclear, but it seems that individuals with low concentrations of plasma Lp(a) manifest no deficiency ...
GALVANO, Fabio +7 more
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Physiopathological Hypothesis of Cellulite [PDF]
A series of questions are asked concerning this condition including as regards to its name, the consensus about the histopathological findings, physiological hypothesis and treatment of the disease. We established a hypothesis for cellulite and confirmed that the clinical response is compatible with this hypothesis.
de Godoy, José Maria Pereira +1 more
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A Comparison between Integrated Courses and Discipline-Based physiopathology Program in Zanjan University of Medical Science [PDF]
Introduction: Medical education in general, and physiopathology teaching program in particular, have undergone a number of changes in recent years. Outcomes of recent reforms performed in undergraduate medical curriculum should be determined. The present
Majid Valizadeh +3 more
doaj
Background Ischemia–reperfusion (Isc/Rep) incidence can damage kidneys and long-distance organs such as the liver. Due to the increasing use of herbs in medicine, this study was designed to assess the effects of Acacetin (ACA) on pathophysiology of liver
Cyrus Jalili +7 more
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Mind the Gap: LRRK2 Phenotypes in the Clinic vs. in Patient Cells
Mutations in the Parkinson’s disease (PD) protein Leucine Rich Repeat Kinase 2 (LRRK2) have been under study for more than 15 years and our understanding of the cellular phenotypes for the pathogenic mutant forms of LRRK2 has significantly advanced.
Liesel Goveas +3 more
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. Low-back pain is one of the most common causes of physical disability, most often originating from intervertebral disc degeneration. Lack of pinpointing the exact source of pain is the limiting factor in more efficient prevention and treatment.
Simeon Grazio +15 more
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Cell kinetics and biochemical parameters in breast cancer
The study analyzes biochemical and cell kinetic parameters to characterize solid tumor growth in humans. The concentrations of polyamines, CEA, the thymidine labeling index (T.L.I.) and the mitotic index (M.I.) were determined on fragments of neoplastic ...
A. Becciolini +7 more
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The Relationship of Stroke and Sleep-A Review
Ischemic stroke appears the third leading cause of mortality and the first cause of disability in developing countries. The relationship between sleep disorders and cerebrovascular risk factors is well defined and there are different mechanisms in ...
Melike Batum +2 more
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SHOCK SYNDROMES ARE OF THREE TYPES: cardiogenic, hemorrhagic and inflammatory. Hemorrhagic shock has its initial deranged macro-hemodynamic variables in the blood volume and venous return. In cardiogenic shock there is a primary pump failure that has cardiac output/mean arterial pressure as initial deranged variables.
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