Results 81 to 90 of about 58,523 (241)

Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes

Cells, 2020
Astrocytes, the most numerous cells of the central nervous system, exert critical functions for brain homeostasis. To this purpose, astrocytes generate a highly interconnected intercellular network allowing rapid exchange of ions and metabolites through ...
Angela Lanciotti, Maria Stefania Brignone, Marcello Belfiore, Sandra Columba-Cabezas, Cinzia Mallozzi, Olimpia Vincentini, Paola Molinari, Tamara Corinna Petrucci, Sergio Visentin, Elena Ambrosini   +9 more
doaj   +1 more source

Loss-of-function genetic diseases and the concept of pharmaceutical targets [PDF]

, 2007
The biomedical world relies heavily on the definition of pharmaceutical targets as an essential step in the drug design process. It is therefore tempting to apply this model to genetic diseases as well.
Laurent Ségalat, MA Lindsay, RR Brinkman, F Sams-Dood, F Sams-Dood, M Ceccarelli, V Dubowitz, TA Rando, G Meister, C Eggert, P Rustin   +10 more
core   +5 more sources

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, Volume 36, Issue 39, 14 May 2026.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Activities of daily living and their neural correlates across the Alzheimer's disease continuum: Evidence from a Latin American cohort

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Functional decline in activities of daily living (ADL)—advanced (AADL), instrumental (IADL), and basic (BADL)—is a hallmark of Alzheimer's disease (AD). However, integrated clinical–neuroanatomical evidence on progression across the AD continuum remains limited, particularly in Latin American populations.
Fernando Henríquez, Patricio Riquelme, Gonzalo Forno, Joaquín Migeot, Rodrigo Henríquez, Patricia Lillo, Daniela Thumala‐Dockendorff, Cecilia Okuma, Cecilia González Campo, Michael Hornberger, Francisco Aboitiz, Andrea Slachevsky   +11 more
wiley   +1 more source

Coronary Artery Spasm: From Physiopathology to Diagnosis

Life
Coronary artery spasm (CAS) is a reversible vasoconstriction of normal or atherosclerotic epicardial coronary arteries with a subsequent reduction in myocardial blood flow, leading to myocardial ischemia, myocardial infarction, severe arrhythmias, or ...
Ilinca Savulescu-Fiedler, Radu Octavian Baz, Radu Andrei Baz, Cristian Scheau, Andrei Gegiu   +4 more
doaj   +1 more source

Aerospace Medicine and Biology: A continuing bibliography (supplement 229) [PDF]

This bibliography lists 109 reports, articles, and other documents introduced into the NASA scientific and technical information system in January ...

core   +1 more source

Seasonal variation of 25-hydroxyvitamin D3 levels in meat of Moroccan onehumped dromedary camels (Camelus dromedaries) [PDF]

, 2015
In human, vitamin D which derives from the action of sunlight in the skin and dietary intake is of great importance for health, and may be influenced by the season.
Abouhafs, Rachid, Bargaa, Rita, El Abbadi, Najia, El Khasmi, Mohammed, Faye, Bernard, Mohamed, F., Tahri, El Hassan   +6 more
core  

Sequence‐Specific Primer Polymerase Chain Reaction Genotyping of Interleukin‐22 Single Nucleotide Polymorphisms rs2227473 and rs2227513 with Validation by Sanger Sequencing

Current Protocols, Volume 6, Issue 5, May 2026.
Abstract Single nucleotide polymorphisms (SNPs) can modify protein expression or function, influencing susceptibility to various diseases. Interleukin‐22 (IL‐22), involved in epithelial barrier homeostasis and tissue repair, has shown complex roles in autoimmune, infectious, and inflammatory conditions.
Julyane Schavaren, Matheus Braga, Aléia Harumi Uchibaba Yamanaka, Guilherme Castellani, Abygail Karlla Donadelli Damico, Louise Fernanda Rosa Frühauf, Liliana Vitoria Dagues de Andrade, Bruna Karina Banin Hirata, Larissa Danielle Bahls Pinto   +8 more
wiley   +1 more source

Fisiopatología de los síndromes coronarios agudos Physiopathology of the acute coronary syndromes

Revista Cubana de Medicina, 2006
En la angina estable crónica, los episodios isquémicos (anginosos o silentes) ocurren fundamentalmente por un incremento de las demandas miocárdicas de oxígeno que exceden la capacidad de aumentar el flujo coronario por una estenosis significativa ...
Javier Almeida Gómez, Orlando Álvarez Toledo   +1 more
doaj  

A neuronal relay mediates a nutrient responsive gut/fat body axis regulating energy homeostasis in adult Drosophila [PDF]

, 2019
The control of systemic metabolic homeostasis involves complex inter-tissue programs that coordinate energy production, storage, and consumption, to maintain organismal fitness upon environmental challenges.
Bauer, Christin, Cordero, Julia B., Kruspig, Bjorn, Maddocks, Oliver D.K., Murphy, Daniel J., Scopelliti, Alessandro, Vidal, Marcos, Yu, Yachuan, Zhang, Tong   +8 more
core   +1 more source