Results 61 to 70 of about 17,475 (188)

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Citrus Peel Xanthophylls Orchestrate Lipid–Glucose–Inflammation Axis Reprogramming in Cardiometabolic Syndrome: Integrative In Silico and In Vivo Evidence

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Central obesity and dyslipidaemia converge to impair insulin signalling and trigger chronic inflammation, oxidative stress, and mitochondrial dysfunction. This integrated metabolic disruption drives lipid imbalance, apoptosis, and persistent hyperglycaemia, ultimately accelerating the progression of type 2 diabetes and cardiovascular disease.
Muhammad Reva Aditya, Muhammad Yusuf, Kanandya Kizzandy, Rizki Hari Mulia, Agnes Vianne, Athaya Rahmanardi Muhammad, Davina Shafa Aviantiputri, Adha Fauzi Hendrawan, Ade Meidian Ambari, Dante Saksono Harbuwono, Antonello Santini, Fahrul Nurkolis   +11 more
wiley   +1 more source

Phytosomes – an Effective Drug-Delivery System. Development, Technology, Application.

Eurasian Chemico-Technological Journal
Herbal ingredients are widely used in practice due to their broad pharmacological effects and absence of side effects. However, despite their remarkable pharmacodynamic activity, most of the herbal ingredients have shown lower bioavailability in vivo ...
I.A. Khabarov, S.D. Sergazy, A.S. Maikenova, A.N. Zhabayeva, O.V. Maslova, S.M. Adekenov   +5 more
doaj   +1 more source

(1S*,3R*,5S*,7S*)-4,4,8,8-Tetrachloro-1-isopropyl-5-methyltricyclo[5.1.0.03,5]octane

Acta Crystallographica Section E, 2014
The title compound, C12H16Cl4, is a derivative of the natural product 1-isopropyl-4-methylcyclohexa-1,4-diene, and represents a diastereomer with two trans-fused cyclopropane rings.
Koblandy M. Turdybekov, Oleg G. Ryazantsev, Gayane A. Atazhanova, Sergazy M. Adekenov   +3 more
doaj   +1 more source

Green Synthesis of Silver Nanoparticles Using Root Extract of Gomphrena vaga Mart.: Metabolomic Insights Into Nanoparticle Formation and Antimicrobial Activity

Nano Select, Volume 7, Issue 8, August 2026.
This study presents the green synthesis of ultrasmall silver nanoparticles using Gomphrena vaga Mart. root extract. The nanoparticles synthesized were stable and showed good broad‐spectrum antibacterial activity against Gram‐positive and Gram‐negative bacteria in initial studies.
Uedson da Silva das Neves, Thyerre Santana da Costa, Symone Costa de Castro, Maelson Cardoso Lacerda, Mauro Alves Bueno, Ljubica Tasic   +5 more
wiley   +1 more source

Innovative and cost-effective SesZen-Bio™ with enriched Biotin and improved superior dissolution efficiency

Journal of Applied Pharmaceutical Research
Background: Micronutrient deficiencies, including biotin, iron, zinc, and vitamin D, can lead to hair problems such as loss and thinning. This study explores the improvement of SesZen-BioTM, a natural biotin supplement derived from Sesbania grandiflora ...
Mihir Gadani, Sneha Badak, Ratna Upadhyay   +2 more
doaj   +1 more source

Assessing ChatGPT for taxonomic and floristic studies

Nordic Journal of Botany, Volume 2026, Issue 8, August 2026.
The advancement of biological sciences has long been closely linked to technological progress. ChatGPT, a generative artificial intelligence chatbot capable of producing human‐like conversational responses, has recently attracted attention as a potential support tool for scientific research.
Mykyta Peregrym, Olena Kozak, Ahmet Emre Yaprak, Alan Elliott, Pedro Bond Schwartsburd, Karime Abidkulova, Anna Voytsekhovich, Olena Danylevska   +7 more
wiley   +1 more source

Phytochemical comparison of selected Sida species using spectrophotometric and multiple chromatographic analyses

Future Journal of Pharmaceutical Sciences
Background Bala is an important Ayurvedic drug used for the treatment of many diseases. Sida cordifolia (L.), Malvaceae family, is the genuine source drug of Bala as per Ayurvedic Pharmacopeia of India.
Cheruthazhakkat Sulaiman, Ankitha Saji, Erayur Mana Anandan, Indira Balachandran   +3 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, Volume 40, Issue 8, Page 4792-4801, August 2026.
ABSTRACT The preclinical evidence for the safety of ashwagandha ( Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports. Most studies and reviews conclude
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Integrating Artificial Intelligence Into Drug Discovery From Medicinal Plants: Current Applications and Infrastructural Challenges

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
This review presents a systems‐oriented roadmap for integrating artificial intelligence into medicinal plant drug discovery to overcome persistent bottlenecks like extract complexity. It highlights that advancing toward reproducible therapeutics requires making phytochemical datasets AI‐ready via rigorous harmonization and phyto‐centric foundational ...
Amit Gangwal, Azim Ansari, Mohd Usman Mohd Siddique, Jyotiram Sawale, Suhas Padmane, Raju Wadekar   +5 more
wiley   +1 more source