Results 61 to 70 of about 18,034 (188)

AIEgen Targets the STAT3‒SUCLG2 Axis to Regulate Metabolism for Colorectal Cancer Theranostics

Aggregate, Volume 7, Issue 6, June 2026.
In CRC, TPA‐FB directly binds to STAT3 and blocks its phosphorylation. It reduces SUCLG2 expression, disrupts mitochondrial function and modulates protein succinylation. Our work highlights that targeting oncogenic STAT3, TPA‐FB rewires metabolism and inhibits CRC progression.
Shaomin Zou, Dan Zhong, Song Xiang, Jieping Zhang, Ruijia Zhang, Ziqing Yang, Manqi Meng, Kuiheng Chen, Ling Fang, Bart Ghesquiere, Hai‐Tao Feng, Ben Zhong Tang, Lekun Fang   +12 more
wiley   +1 more source

A Review of the Ethnomedicine, Phytochemistry, Pharmacology and Toxicological Studies on Ptaeroxylon obliquum (Thunb.) Radlk. (Rutaceae)

Ptaeroxylon obliquum (Thunb.) Radlk. (Rutaceae) is traditionally used for a range of purposes, including ethnoveterinary medicine and to treat various human ailments such as tuberculosis, inflammatory diseases, and bacterial and fungal infections.
Edward Thato Khunoana, Thanyani Emelton Ramadwa, Sanah Malomile Nkadimeng, Ntanganedzeni Makumbane   +3 more
core   +1 more source

Terebenthifolic Acid And Bauerenone: New Triterpenoid Ketones From Schinus Terebenthifolius

, 2015
[No abstract available]141023002302Kaistha, Kier, (1962) J. Pharm. Sci., 51, p. 145Kaistha, Kier, (1962) J. Pharm. Sci., 51, p. 1136Kier, Lehn, Ourisson, (1963) Bull. Soc. Chim. Fr., p.
de Paiva Campello J., Marsaioli A.J.
core   +1 more source

Metabolomic Differentiation of Malpighiaceae From Dry and Humid Tropics via UHPLC‐MS/MS and Chemometrics

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Various factors can trigger water stress in plants, particularly in those growing in dry tropical regions. To survive under such conditions, plants produce metabolites with adaptive functions. However, metabolomic data on the leaves of Malpighiaceae species cultivated in both dry and humid tropical areas of Brazil remain scarce.
Jaqueline Munise Guimarães da Silva, Rafael Felipe de Almeida, Maria Luiza Zeraik   +2 more
wiley   +1 more source

13c Nmr Analysis Of Aporphine Alkaloids

, 2015
The 13C NMR spectra of some tertiary and quaternary aporphine alkaloids are recorded and the signals assigned. The substituent shielding effects together with the effects of N- and O-methylation, and the twisting of the biphenyl system, are analysed and ...
Kuck A.M., Marsaioli A.J., Magalhaes A.F., Ruveda E.A., de A.M. Reis F.   +4 more
core   +1 more source

Population‐Specific Chemotypes in Pseudomisopates rivas‐martinezii (Sanchez Mata) Güemes From La Serrota and Gredos Massifs (Iberian Central Range)

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Pseudomisopates rivas‐martinezii, a critically endangered Iberian endemic, reveals population‐specific chemotypes when analyzed by elemental analysis, FTIR, and GC–MS. Underground tissues from both populations share a convergent histidine‐derived metabolite profile, whereas aerial parts diverge markedly: La Serrota accumulates phenolic derivatives from
Eva Sánchez‐Hernández, María Elena Amat, Mario Cano‐Pérez, Vicente González‐García, Jesús Martín‐Gil, Pablo Martín‐Ramos   +5 more
wiley   +1 more source

The Influence of Sexual Polymorphism on Metabolomics and Biological Activities of Pawpaw (Carica papaya)

Scientifica
Pawpaw (Carica papaya) is an economically important tropical crop valued for its nutritional fruit. The leaf is eaten as salad, soup, or tea. Various parts of the pawpaw are used to treat diseases.
Emmanuel Kofi Kumatia, Ebenezer Ehun, Anne Boakyewaa Anokye-Kumatia   +2 more
doaj   +1 more source

Comparative Phytochemical Analysis of Five South African Bulbine Species Using Chromatography‐Based Methods

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Comprehensive chromatographic and chemometric profiling of five medicinal South African Bulbine species across leaves, rhizomes, and roots reveals 73 metabolites, including species‐specific phenylanthraquinones, flavonoids, and anthocyanins, that serve as reliable chemical markers for species authentication.
Ramoagi T. Segone, Maxleene Sandasi, Efficient Ncube, Weiyang Chen, Bharathi Avula, Kumar Katragunta, Ikhlas A. Khan, Alvaro M. Viljoen   +7 more
wiley   +1 more source

Phytochemistry

, 2013
Texto completo. Acesso restrito. p. 71–77The plant Cecropia pachystachya Trécul is widely used in Brazilian ethnomedicine to treat hypertension, asthma, and diabetes.
Cruz, Ebenézer de Mello, Reis, Matheus Balduino Gonçalves dos, Santos, Marcos André Vannier dos, Lucon Junior, João Francisco, Alves, Eliomara Sousa Sobral, Silva, Edson Roberto da, Maquiaveli, Claudia do Carmo, Toledo, Cleyton Eduardo Mendes de, Cruz, Frederico Guare   +8 more
core  

Antioxidant Activity and Inhibition of Carbohydrate Hydrolyzing Enzymes by Underutilized Parts From Some Plant‐Based Foods and Their Effect on Postprandial Hyperglycemia

Food Chemistry International, Volume 2, Issue 2, Page 285-294, June 2026.
The underutilized parts viz: pawpaw seed, banana, plantain, and potato peels showed promising antioxidant and inhibition of α‐amylase and α‐glucosidase activities (IC50 values ≤ 100 μg/mL). Similarly, pawpaw seed, banana, plantain, and potato peels reduced postprandial hyperglycemia in sucrose‐ and maltose‐induced hyperglycemia in rats.
Aminu Mohammed, Buhari Shehu Saidu, Nuhu Aliyu, Michael Peter Simon   +3 more
wiley   +1 more source