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Annual Review of Plant Biology, 2004 ▪ Abstract Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals. These compounds, termed phytoestrogens, include certain isoflavonoids, flavonoids, stilbenes, and lignans.
Adlercreutz H +37 more
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Therapeutic potential of common Phytoestrogens found in traditional Chinese medicine in chronic kidney diseases [PDF]
Frontiers in PharmacologyIn recent years, phytoestrogens in traditional Chinese medicine (TCM)—a class of estrolike active components naturally occurring in medicinal plants—have gradually emerged as a research hotspot in the treatment of various diseases due to their multi ...
Tongtong Liu, Minghan Li
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Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats [PDF]
Nutrition & Metabolism, 2010 Background Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors.
Kaphalia Bhupendra S +4 more
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Estrogenic Effect of Various Plant Extracts on Eel (Anguilla japonica) Hepatocytes [PDF]
MoleculesEstrogen plays some important roles in many physiological processes in animals. This hormone is used as a type of medication for humans and animals, including fish, but is associated with serious side effects and environmental persistence, which has led ...
Jeong Hee Yoon +2 more
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SIRT1/DNMT3B-mediated epigenetic gene silencing in response to phytoestrogens in mammary epithelial cells [PDF]
EpigeneticsWe performed an integrated analysis of genome-wide DNA methylation and expression datasets in normal cells and healthy animals exposed to polyphenols with estrogenic activity (i.e. phytoestrogens). We identified that phytoestrogens target genes linked to
Yuexi Ma +5 more
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Journal of Medicinal Plants, 2007 Epidemiological studies suggest that populations consuming a diet of high phytoestrogens, have a lower risk of many of the so-called “western” diseases.Phytoestrogens are naturally found in many foods and their biological activity is confirmed in animals,
M Azadbakht
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Bioactives for Estrogen-Deficient Skin: Topical and Oral Supplement Clinical Studies. A Narrative Review [PDF]
Dermatology and TherapyBioactive compound applications by topical or oral administration have gained increased utilization/awareness in providing health benefits particularly due to changes in hormone levels and aging, especially in women with the decline and loss of estrogens.
Edwin D. Lephart
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Dietary Phytoestrogens and Their Metabolites as Epigenetic Modulators with Impact on Human Health
Antioxidants, 2021 The impact of dietary phytoestrogens on human health has been a topic of continuous debate since their discovery. Nowadays, based on their presumptive beneficial effects, the amount of phytoestrogens consumed in the daily diet has increased considerably ...
Victor Stefan Ionescu +5 more
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Journal of Advanced Veterinary and Animal Research, 2023 Phytoestrogens are non-steroid polyphenolic materials present in 300 plants. Regarding their structural similarities to estradiol, phytoestrogens attach to estrogen receptors and display anti-or pro-estrogenic activities.
Safaa I. Khater +8 more
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Estrogenic Pastures: A Source of Endocrine Disruption in Sheep Reproduction
Frontiers in Endocrinology, 2022 Phytoestrogens can impact on reproductive health due to their structural similarity to estradiol. Initially identified in sheep consuming estrogenic pasture, phytoestrogens are known to influence reproductive capacity in numerous species.
Kelsey R. Pool +3 more
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