Results 171 to 180 of about 47,579,310 (326)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Delta Sigma Pi certificate

open access: yes, 1963
Membership certificate for Smith Green in Delta Sigma ...
Delta Sigma Pi
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Polymerases Pi − 1, Pi, and Pi+1 in order on the DNA strand.

open access: yes, 2016
Heberling Tamra   +4 more
semanticscholar   +1 more source

Delta Sigma Pi pin

open access: yes, 1961
Delta Sigma Pie scholarship key. On reverse: "Delta Sigma Pi Scholarship Key Texas Christian University Awarded to Smith L.
Delta Sigma Pi
core  

Geopolitics and Energy Security: A Comprehensive Exploration of Evolution, Collaborations, and Future Directions

open access: yes
This database is used to store source data, table files and chart files used in ...
pi, pi
core   +1 more source

Pi 1 pulsations associated with substorms and their conjugate behavior

open access: yesPi 1 pulsations associated with substorms and their conjugate behavior
P(論文) Short period geomagnetic pulsations associated with substorms in the frequency range from about 0.1 to 0.4Hz are investigated using the dynamic spectrum analysis technique, and it was found that these Pi 1 pulsations are excited simultaneously with Pi 2 pulsations and they show a clear conjugate behavior.
openaire  

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