Results 161 to 170 of about 880,343 (275)

Novel two-stage deep learning framework for automated pressure injury classification. [PDF]

BMJ Health Care Inform
Lai TY, Chou YJ, Liu CY, Chen CW, Lin CT, Wang WC, Hsu Y, Hsieh ML, Chang SS.   +8 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Research on the Synthesis and Characterization of Colorless Polyimide Based on a Novel Asymmetric Dianhydride Monomer. [PDF]

ACS Omega
Liu J, Wang Y, Tu G.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Spinopelvic-Hip Harmony [PFA-(PI-LL)] as a Radiographic Indicator of Hip Extension Compensatory Reserve in Kyphotic Adult Spinal Deformity: A Multicenter Study. [PDF]

Global Spine J
Ishikawa K, Takahashi K, Hashimoto K, Yahata K, Baba K, Onoki T, Fujita R, Kusakabe J, Kawaharada T, Sato M, Nakamura T, Sugawara R, Handa K, Kanno H, Ozawa H, Tanaka Y, Aizawa T.   +16 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Intraoperative Peripheral Iridotomy for Endothelial Keratoplasty with a 22-Gauge Needle. [PDF]

Eye Bank Corneal Transpl
Rustam Z, Agrawal A, Kulkarni R, Mohamed F, Thomas J, Choi J, Wang C, Ansah DO, Fan P, Mitra PR, Yearis K, Woreta FA, Srikumaran D, Eghrari AO.   +13 more
europepmc   +1 more source

Gut microbiota and Ma-Pi 2 macrobiotic diet in the treatment of type 2 diabetes. [PDF]

World J Diabetes, 2015
Fallucca F, Fontana L, Fallucca S, Pianesi M.   +3 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source