Results 201 to 210 of about 4,298,011 (325)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

DÍMERO-D COMO IMPORTANTE MARCADOR PARA ESTRATIFICAR A GRAVIDADE DA INFECÇÃO PELO NOVO CORONAVÍRUS: REVISÃO SISTEMÁTICA DA LITERATURA

open access: yesHematology, Transfusion and Cell Therapy, 2020
L.C. Bruno   +9 more
doaj   +1 more source

Cortisol treatment impairs path integration and alters grid-like representations in the male human entorhinal cortex. [PDF]

open access: yesPLoS Biol
Akan O   +6 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

RELAÇÃO ENTRE A DEFICIÊNCIA NA TRIAGEM NEONATAL E A FALHA NO DIAGNOSTICO PRECOCE DAS HEMOGLOBINOPATIAS: REVISÃO DE LITERATURA

open access: yesHematology, Transfusion and Cell Therapy, 2020
I.D. Rêgo   +9 more
doaj   +1 more source

Novel two-stage deep learning framework for automated pressure injury classification. [PDF]

open access: yesBMJ Health Care Inform
Lai TY   +8 more
europepmc   +1 more source

On stabilizing hydraulic motion experiencing Stribeck friction via PI controller: Circle criterion approach

open access: diamond, 2019
Tobias Prawira Tumbuan   +3 more
openalex   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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