Results 161 to 170 of about 219,177 (262)

Spatial Distribution of Prostate Cancer Missed by MRI-Targeted Biopsy, Effect of a Perilesional Template, and Restaging in a Radical Prostatectomy Cohort. [PDF]

Prostate
Himmelsbach R, Franz J, Jilg C, Gratzke C, Sigle A.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Arterial and Venous Doppler Parameters in Fetal Growth Restriction: A Comparative Evaluation of Early- and Late-Onset Subtypes. [PDF]

Diagnostics (Basel)
Ankara Aktas H, Gercik Arzik I, Emiralioglu Cakir Z, Bayraktar B, Konuralp Atakul B, Bayram E, Timur ES, Omeroglu I, Ekin A, Golbasi H.   +9 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

In Vivo Assessment of Placental Structure and Perfusion in Late-Gestation Pregnancies and Their Association With Fetal Growth. [PDF]

NMR Biomed
Link-Sourani D, Avisdris N, Shao X, Schonberger D, Rabinowich A, Fadida BS, Wexler Y, Joskowicz L, Sira LB, Hiersch L, Wang DJJ, Bashat DB.   +11 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Analysis of baseline sagittal balance indicators and compensatory mechanisms at adult degenerative scoliosis in elderly patients operated on minimally invasive lateral lumbar interbody fusion. [PDF]

J Craniovertebr Junction Spine
Klimov VS, Kivelev JV, Amelina EV, Evsukov AV, Krivoshapkin AL, Ryabykh SO, Kalinin AA, Byvaltsev VA.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Assessment of parasacral ischial plane block success using sonographically measured regional hemodynamic variables and perfusion index: an observational diagnostic accuracy study. [PDF]

BMC Anesthesiol
Raina R, Bhatia N, Jain K, Nair R, Mahajan V, Arora S, Aggarwal S, Hazarika A.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source