Results 151 to 160 of about 6,027,070 (293)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

The efficacy of different ultrasound Doppler parameters in predicting adverse fetal outcomes in pregnancies with hypertensive disorders: a systematic review and meta-analysis. [PDF]

Quant Imaging Med Surg
He X, Yang F, Zhang K.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Transrectal spectral Doppler reveals uterine hyperemia in Tharparkar cows with subclinical endometritis. [PDF]

Front Vet Sci
Sahu UK, Kumar B, Khan MH, Singh M, Warghat C, Vadera V, Kumar A, Reddy AL, Kharayat NS, Vandana, Chouhan VS, Rajput P, Kumar M, Sahu L, Verma H, Sahu G, Singh SK.   +16 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Beyond biometry: the role of fetal venous doppler in discriminating fetal growth restriction from small for gestational age and predicting adverse perinatal outcomes. [PDF]

BMC Pregnancy Childbirth
Filiz AA, Karabay G, Çakir BT, Kından A, Aktemur G, Şeyhanlı Z, Lekesiz B, Sümer D, Dağdeviren G.   +8 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Revan Index, PI Index and Revan Weighted PI Index of Möbius Function Graphs: A Comparative Study

Journal of Informatics and Mathematical Sciences
Rani Jose, D. Susha, Meerra Sajeev
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Gingival Enlargement Induced by Orthodontic Therapy: A Systematic Review. [PDF]

Int J Dent
Rocha-Eiroa MD, Ramírez-Rámiz A, Brunet-Llobet L, Cahuana-Bartra P, Rabassa-Blanco J, Miranda-Rius J.   +5 more
europepmc   +1 more source