Results 121 to 130 of about 25,215 (225)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, Volume 20, Issue 8, Page 2023-2039, August 2026.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Integrated Hemodynamic Measures of Cardiac Function and Association With Clinical Outcomes. [PDF]

JACC Adv
Trad OK, Parekh JK, Kosyakovsky LB, Mounsey L, Pomerantsev EV, Picard MH, Quintero Pinzon PA, Sabe M, Grandin EW, Garan AR, Ho JE.   +10 more
europepmc   +1 more source

Interstitium‐Mimicking Porous Alveolar Membranes Enable Physiologic Aerosol Transport and Distinct Acute‐Chronic Lung Injury Responses

Advanced Functional Materials, Volume 36, Issue 62, 3 August 2026.
An interstitium‐mimicking membrane combines three‐dimensional alveolar geometry, high pore interconnectivity, and mechanical compliance to overcome transport limitations of conventional lung‐on‐chip barriers. The resulting platform supports physiologic aerosol transport, quantitative analysis of cross‐barrier particle movement, and reveals divergent ...
Jae‐Won Choi, Sheng Zhang, Abbas Jalili, August Kohls, Woo‐Youl Maeng, Sikandar Azam, Wu Liu, Barbie Varghese, Yixin Zhao, Xi Ren, Shimin Liu, Si‐Yang Zheng   +11 more
wiley   +1 more source

Undernutrition Risk in Community-Living Older Adults: Post-COVID-19 Results from the 2023 U.S. National Survey of Older Americans Act Participants. [PDF]

Nutrients
Dwyer JT, Gahche JJ, Arensberg MB, Borth L, Chao S, Simon J, McGrath L, Picard A.   +7 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, Volume 13, Issue 43, 3 August 2026.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Evaluating the Immune Response in Rabbits to an Escalating Dose of mRNA-Based HIV-1 Env Immunogens. [PDF]

Vaccines (Basel)
Ahmed S, Parthasarathy D, Picard TC, Matyas GR, Rao M, Herschhorn A.   +5 more
europepmc   +1 more source

Altered Evening Aperiodic Activity and Microstate Dynamics in Insomnia Disorder: An OPM MEG Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Using wearable OPM‐MEG, this study characterized evening and morning resting state neurophysiology in insomnia disorder. A flatter evening aperiodic spectral exponent suggested relatively elevated cortical excitability, alongside altered microstate dynamics involving putative limbic and sensorimotor network states.
Feng Cui, Kejia Hu, Hui Zeng, Yang Wang, Xi Wang, Haiting Liu, Tangfen Wang, Yan Chang, Xiaodong Yang, Tao Hu, Tianxiao Shen, Jianbing Zhu, Jian Zheng, Donghua Pan   +13 more
wiley   +1 more source

Invariant Measure and Universality of the 2D Yang–Mills Langevin Dynamic

Communications on Pure and Applied Mathematics, Volume 79, Issue 8, Page 1973-2102, August 2026.
ABSTRACT We prove that the Yang–Mills (YM) measure for the trivial principal bundle over the two‐dimensional torus, with any connected, compact structure group, is invariant for the associated renormalised Langevin dynamic. Our argument relies on a combination of regularity structures, lattice gauge‐fixing and Bourgain's method for invariant measures ...
Ilya Chevyrev, Hao Shen
wiley   +1 more source

Inter-Regional Center for Automated Insulin in Diabetes (CIRDIA) and Hospital-Based Approaches to Closed-Loop Therapy in Type 1 Diabetes: Cost-Effectiveness Analysis. [PDF]

JMIR Diabetes
Napame M, Picard S, Foglia T, Rubenstrunk A, Baudoux F, Giroud F, Lablanche S, Borot S.   +7 more
europepmc   +1 more source

Intestinal epithelial SETD2 maintains gut microbial homeostasis to attenuate colitis

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• SETD2 deficiency in intestinal epithelial cells (IECs) drives REG3 lectins overproduction and triggers profound gut microbiota dysbiosis. • SETD2 deficiency increased chromatin accessibility and induced H3K4me3 enrichment at REG3 genes. • Supplementation with healthy‐like gut microbiota significantly ameliorated the exacerbated colitis induced by ...
Jing Feng, Ziyi Wang, Yue Xu, Jinjin Peng, Che Xu, Qingxin Xie, Yuyi Li, Wangshuang Chen, Jiaqing Chen, Xingyu Wang, Wei‐Qiang Gao, Li Li, Xiangjun Meng   +12 more
wiley   +1 more source