Results 51 to 60 of about 3,143 (223)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Metaheuristics for the Order Batching Problem in Manual Order Picking Systems [PDF]
In manual order picking systems, order pickers walk or drive through a distribution warehouse in order to collect items which are requested by (internal or external) customers.
Christine Strauss +4 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Travel Time Estimation and Order Barching in a 2-Block Warehouse [PDF]
, 2004 The order batching problem (OBP) is the problem of determining the number of orders to be picked together in one picking tour. Although various objectives may arise in practice, minimizing the average throughput time of a random order is a common concern.
Koster, M.B.M. (René) de +1 more
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
High-Level Object Oriented Genetic Programming in Logistic Warehouse Optimization [PDF]
, 2014 Disertační práce je zaměřena na optimalizaci průběhu pracovních operací v logistických skladech a distribučních centrech. Hlavním cílem je optimalizovat procesy plánování, rozvrhování a odbavování.
Karásek, Jan
core
From bricks-and-mortar to bricks-and-clicks: logistics networks in omni-channel grocery retailing [PDF]
, 2018 Purpose: The advent of grocery sales through online channels necessitates that bricks-and-mortar retailers redefine their logistics networks if they want to compete online. Because the general understanding of such bricks-and-clicks logistics systems for
Hübner, Alexander +3 more
core +2 more sources
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Instances for the picker routing problem in U-shaped warehouses (PRP-UW)
, 2021 Heiko Diefenbach +3 more
openalex +3 more sources
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source